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作者：林赴田
比阿培南|抗菌活性|药代动力学|临床疗效|毒副反应
作者：林赴田
单位：中国医学科学院 中国协和医科大学医药生物技术研究所，北京 100050
关键词：比阿培南；抗菌活性；药代动力学；临床疗效；毒副反应
中国新药杂志990104 摘要 综述比阿培南体外和体内抗菌作用及其对β-内酰胺酶的稳定性、毒性、药代动力学和临床应用。
PHARMACOLOGY AND CLINICAL USES OF BIAPENEM，A NEW CARBAPENEM
Lin Futian
(Institute of Medical Biotechnology,Chinese Academy of
Medical Sciences,Beijing 100050)
ABSTRACT The in vitro and in vivo antibacterial activities,the stability to β-lactamase,the toxicity,the pharmacokinetics,and the clinical uses of biapenem were reviewed.
KEY WORDS Biapenem ;Antibacterial activity;Pharmacokinetics;Clinical effects；Side reaction
碳青霉烯类(Carbapenems)属于β-内酰胺全新结构的抗生素 ......
单位：中国医学科学院 中国协和医科大学医药生物技术研究所，北京 100050
关键词：比阿培南；抗菌活性；药代动力学；临床疗效；毒副反应
中国新药杂志990104 摘要 综述比阿培南体外和体内抗菌作用及其对β-内酰胺酶的稳定性、毒性、药代动力学和临床应用。
PHARMACOLOGY AND CLINICAL USES OF BIAPENEM，A NEW CARBAPENEM
Lin Futian
(Institute of Medical Biotechnology,Chinese Academy of
Medical Sciences,Beijing 100050)
ABSTRACT The in vitro and in vivo antibacterial activities,the stability to β-lactamase,the toxicity,the pharmacokinetics,and the clinical uses of biapenem were reviewed.
KEY WORDS Biapenem ;Antibacterial activity;Pharmacokinetics;Clinical effects；Side reaction
碳青霉烯类(Carbapenems)属于β-内酰胺全新结构的抗生素 ......