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编号:10416471
Chin Crit Care Med,April 2004,Vol.16,No.4
http://www.100md.com 2004年4月12日 急救快车
     PAGE:193-197

    Changes in human leukocyte antigen-DR expression on monocytes and its value of prediction on infection complication in trauma patients

    Hu Cheng-xiang, Xu Xiang, Liang Hua-ping, Lu Feng-lin, Shen Li-qun, Hao Tian-zhi

    Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China

    OBJECTIVE: To observe the changes of human leukocyte antigen DR(HLA-DR) expression in monocytes of trauma patients and its value of prediction on infection complications. METHODS: Fifty-four trauma patients were divided into three groups according to severity of injury: severe trauma group 〔injury severity score(ISS)≥25〕, moderate trauma group (16≤ISS<25) and mild trauma group (ISS<16). In addition, 34 severe trauma patients (ISS≥16) were divided into three groups according to infection or not: no infection group, localized infection group and systemic infection group. Blood samples were collected immediately after admission and serially at 8:30 to 9:00 a.m.on days 1, 2, 4, 6, 8, 14 after admission, and monocyte HLA-DR expression was determined with monoclonal staining and flow cytometry. RESULTS: The HLA-DR expression in monocytes was reduced in the trauma patients. The lowest levels of HLA-DR were recorded on day 2 after trauma. Subsequently HLA-DR expression in monocytes increased gradually. During the whole observation, the HLA-DR expression was significantly decreased in both severe trauma group and moderate trauma group versus control group, but no significant differences were found between severe trauma group and moderate trauma group, mild trauma group and control group. Immediately after trauma, HLA-DR expression in monocytes was significantly lower in the localized infection group than that in the patients without infection, and lasted until day 4 after trauma. The mean fluorescence intensity of HLA-DR expression in monocytes on the day 2 to 14 after trauma, the percentage of HLA-DR monocytes on the day 1 to 14 after trauma were significantly lower in the systemic infection group than those in the localized infection group. The level of HLA-DR expression in monocyte in the 2 died trauma patients was lowered till died. CONCLUSION: In severe trauma patients, the HLA-DR expression in monocytes is significantly decreased, and decreased levels of HLA-DR expression in monocytes might be the early indicators of an immune deviation associated with the development of infection complications and prognosis.
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    PAGE:198-201

    An early comprehensive prevention and treatment of sepsis in severely burned patients with delayed fluid resuscitation

    Wu Zu-huang, Liu Min, Xia Zhao-fan, Zhan Xin-hua, Liu Shi-kang

    Department of Burn and Plastic Surgery, The 95 th Hospital of PLA, Putian 351100, Fujian, China

    OBJECTIVE: To study an early comprehensive prevention and treatment of sepsis in severely burned patients with delayed fluid resuscitation. METHODS: From January 1990 to December 2001, 72 cases of patients with delayed fluid resuscitation were admitted to our burn department. Two different periods were divided and analyzed retrospectively. The first period was from January 1990 to December 2001 and the span of the second period was from January 1995 to December 2001. RESULTS: (1)The mortality rate and incidence of sepsis in the second period (6.5 percent and 17.4 percent) were significantly lower than those of the first period(23.0 percent and 57.7 percent, P<0.05 and P<0.01). (2)The time of wound healing in the second period was(1.9±0.9) hours, it was lower than that of the first period (6.6±2.5) hours. (3)The serum contents of tumor necrosis factor(TNF) and blood lactic acid(BLA) were increased at all times in two periods and were markedly increased in the first period (all P<0.01). CONCLUSION: Our data demonstrated that measures adopted in the second period for patients with delayed fluid resuscitation, including early excision, early rapid adequate resuscitation, early enteral feeding, increased immunity function, early applying antibactials, xenotransfusion of ultrariolet-irradiated blood, application of recombinant human-growth factor (rh-GH), epidermal growth factor(EGF), basic fibroblast growth factor (bFGF), are beneficial to the prevention and treatment of sepsis in severely burned patients with delayed fluid resuscitation.
, 百拇医药
    PAGE;202-205

    Immunohistochemical study of fibronectin in multiple organ dysfunction syndrome in elderly rats

    Li Yan-rong, Jing Hua-lan, Cheng Jian-ding, Luo Si-min, Jiang Fu-xue, Zhang Yi-jun

    Department of Forensic Pathology, Sun Yat-sen University, Guangzhou510080, Guangdong, China

    OBJECTIVE: To study the characteristic of endothelial injuries and the mechanisms of coagulation disorder in multiple organ dysfunction syndrome in elderly rats by observing the distribution and the intensity of fibronectin(FN) expression in important viscerae including the heart, brain, lung, kidney, liver. METHODS: Fifty Wistar rats (one half of them were 3 months old, another half 20 months old) were anaesthetized and cecal ligation puncture (CLP) was done. They were defined as MODS group and MODSE group. Forty Wistar rats (one half of them 3 months old, another half 20 months old) were anaesthetized and laparotomy was done as sham operation group (SOG) and sham operation group in elderly (SOGE). The heart, brain, lung, liver and kidney were harvested and were examined histologically at 6, 12, 24, 48 or 72 hours after operation. They were also stained immunohistochemically by using anti-FN as the first antibody. RESULTS: The expression of FN on the surfaces of vascular endothelial cells in hearts, brains, lungs, livers, kidneys was weakly positive or positive in MODSE, MODS or SOGE group, but it was positive or strongly positive in SOG group. The differences were significant (P<0.05). CONCLUSION: The injury of endothelial cells and the disorders of coagulation system are observed in MODSE, MODS, SOGE groups, especially in MODSE.
, 百拇医药
    PAGE:205

    Change of conteats of interleukin-2.6 and 16 in serum of patients with closed craniocerebral injury and its significance

    Luo Xian-rong, Luo Xu-jian, Zhang Yong

    458 th Hospital of PLA, Guangzhou 510602, China

    PAGE:206-209

    Expression characteristics of transforming growth factor-β1 in human skin at different development stages of gestation
, 百拇医药
    Chen Wei, Fu Xiao-bing, Ge Shi-li, Sun Tong-zhu, Jiang Du-yin, Zhou Gang, Sheng Zhi-yong

    Key Research Laboratory of Wound Repair, Burns Institute, 304 th Hospital of PLA, Beijing 100037, China

    OBJECTIVE: To investigate gene expression of transforming growth factor-β1 (TGF-β1) and its two upstream signalling factors (smad2 and smad3) in fetal skin at different gestational ages and postnatal skin and its potential biological significance. METHODS: Fetal skin samples of human embryo were obtained from spontaneous abortions at different gestational ages ranging from 13 to 32 weeks, and also skin collected from patients undergoing plastic surgery. After morphological characteristics of skin at different developmental stages were examined histologically, gene expressions of TGF-β1, smad2 and smad3 in skin specimens at different developmental stages were examined with reverse transcription-polymerase chain reaction analysis (RT-PCR). RESULTS: Gene expression of TGF-β1, smad2 and smad3 could all be detected in fetal skin and skin after birth. In skin from early gestational fetus, gene expressions of TGF-β1 and smad2 were weak. Along with advance in gestational age, gene expression of these two genes in skin became progressively stronger. In skin from late gestational fetus and skin after birth, the transcription contents of these two genes were significantly increased compared with early gestation fetus (P<0.05). On the contrary, gene expression of smad3 was apparently higher in younger fetal skin versus elder compared with that of late fetal skin (P<0.05). In skins after birth, the levels of smad3 gene expression were elevated to the level similar to that in early gestational fetal skin. CONCLUSION: The signal pathway mediated by TGF-β1 might be involved in regulating development of the skin at embryonic stage and in designating cetaceous structure and function, and also in wound healing after birth. The relative lack in expression of TGF-β1 and smad2 genes in skins from younger fetuses might contribute to fetal scar-less healing, in which the role of smad3 needs to be further investigated.
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    PAGE:209

    Improvement of Fixation for oral pharynx snorkel

    Zheng Hong, Li Yan, Li Yue

    The First Center Hospital, Baoding 071000, Heibei, China

    PAGE:210-213

    Influence of hypertonic medium on aquaporin 4 mRNA expression in astrocytes in vitro

    Li Yan-hua, Sun Shan-quan
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    Department of Neurobiology, Chongqing University of Medical Science, Chongqing 400016, China

    OBJECTIVE: To investigate the expression of aquaporin 4(AQP4) mRNA and the role in cultured rat astrocytes after exposured to hypertonic medium. METHODS: Rat cerebral cortical astrocytes from 2-day newborn Wistar rats were seperated for the pure culture in vitro and the model of cell dehydration was established by exposed cultured astrocytes to hypertonic medium. The reactivity and rules of AQP4 mRNA expression of astrocytes to hypertonic medium were studied by in situ hybridization, the activity of lactate dehydrogenase (LDH) was detected, and image was analyzed. RESULTS: After astrocytes cultured for 3, 6, 12, 24 hours with hypertonic medium (320, 333 and 345 mmol/L), the activity of LDH showed a significant increase than that in the control group after astrocytes exposed to hypertonic medium (all P<0.05). In situ hybridization analysis confirmed that the expression of AQP4 mRNA was markedly increased, and especially it was significantly increased in hypertonic medium for 12 hours. CONCLUSION: The cell viability is significantly decreased and the expression of AQP4 mRNA is remarkably increased in hypertonic medium. The result suggests that AQP4 plays an important role in the early stage of the hypertonic dehydration.
, 百拇医药
    PAGE:213

    The Understanding About The Liquid Supply Of Blood Dialysis For Acute Drug Poisioning

    Jiang Zhen-hua, Ren Yue-qing, Shi Guan-mao, Liang Peng-yuan

    The General Hospital of Yangquan Coal Group, Shanxi 045000, China

    PAGE:214-217

    Neurobehavior changes of rats after diffuse axonal injury and the treatment effect with cyclosporin A
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    Yin Wei-dong, Xu Bai-nan, Wang Xiao-gang

    Department of Neurosurgery, General Navy Hospital of PLA, Beijing 100037, China

    OBJECTIVE: To observe rat's memory and learning behavior after diffuse axonal injury (DAI) and evaluate the treatment efficacy of cyclosporin A (CsA). METHODS: Twenty-four SD rats were divided into three groups: non-injured group (n=8), vehicle-treated group (n=8) to whom saline was applied and CsA-treated group (n=8). By analyzing behavior changes of rats in Morris water maze and dark-avoidance test, the CsA treatment efficacy was evaluated. RESULTS: The Morris water maze was used to observe rats' memory and learning behavior. During a place-training experiment, the latency to find platform in each trial descended remarkably. Vehicle-treated group exhibited acquisition deficits compared with CsA-treatment group. The latency in each trial was longer in vehicle-treated group (F=60.44, P<0.01). With continued training, the rats' performance in CsA-treatment group was better than those in control brain-injured group in crossing platform test(F=-4.00, P<0.01), but no difference with the normal group. In dark-avoidance test, the rats in normal control group had remembered the electricity shock very fast, and seldom entered into dark chamber. The mean latency time was (292.88±12.61)seconds. The latency time of rats in CsA-treated group was (224.75±55.95) seconds. The latency time of rats in vehicle-treated group was (153.25±69.36) seconds. The time of rats in CsA-treated group was shorter than the time of vehicle-treated group animal(F=-71.50,P<0.05). CONCLUSION: The rats' memory function is impaired after DAI. The learning acquisition and memory retention impairments are ameliorated after administration of CsA.
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    PAGE:218-220

    Changes of neuropeptide Y activity in plasma and brain tissue during intracerebral hemorrhage in rats 

    Xu Zhi-qiang, Chen Man-e, Jiang Xiao-jiang, Wang Jing-zhou.

    Third Department of Neurology, Daping Hospital, Field Surgery Institute, Third Military Medical University, Chongqing 400042, China

    OBJECTIVE: To evaluate the significance of changes of neuropeptide Y (NPY) activity in plasma and brain tissue during experimental intracerebral hemorrhage(ICH). METHODS: Seventy Wistar rats were randomly divided into two groups: control group and ICH group with each group subdivided into preoperation, 0.5 hours, 6 hours, 12 hours ,24 hours, 48 hours and 72 hours postoperation subgroups, respectively (n=5). The ICH was established by infusing collagenase and heparin into rat caudate. The changes of NPY in plasma and perihemotoma at preoperation, 0.5 hours, 6 hours, 12 hours, 24 hours, 48 hours and 72 hours after operation were observed, respectively. NPY was determined by radio-immunoassay. The morphologic change of brain was detected. RESULTS: NPY activity in plasma and perihematoma increased synchronously after cerebral hemorrhage, and peaked at 24 hours, then began to reduce in 48 hours, it was still higher than those of preoperation at 72 hours after hemorrhage (P<0.05 or P<0.01). The correspondent pathological changes were observed in brain tissue under light microscope and electron microscope. CONCLUSION: NPY might be involved in the pathogenesis of cerebral hemorrhage.
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    PAGE:221-222

    Clinical significance of serum S-100B protein in severe cerebral injury 

    Hu Dian-lei, Liu Xian-hua, Yu Xiao-liang, Guo Hong-mei, Guo Bing, Shi Yan, Zhuang Hui-lin, Shi Peng.

    Department of Neurosurgery, Xuzhou Third Hospital, Xuzhou 221005, Jiangsu, China

    OBJECTIVE: To investigate the value of S-100B protein as a biology marker in diagnosis and prognostic after severe cerebral injury. METHODS: Sixty-six patients with severe head injury〔Glasgow coma scale score(GCS)≤8〕 were included in this study, venous blood samples for S-100B protein were obtained as soon as possible after admission and every 24 hours thereafter for a maximum of 3-7 consecutive days. Serum levels of S-100B protein were compared with outcome (Glasgow outcome scale score, GOS) after 6 months. RESULTS: Of 66 patients, 25 patients died, mutilation in 22 patients, 19 patients had a good outcome. Patients who died had significantly higher serum S-100B values compared with those who survived (median 2.60 μg/L vs. 0.55 μg/L, P<0.001), 14 of 25 patients who died had peak S-100B values of 2.00 μg/L or higher, compared with 4 of 41 surviving patients (P<0.005). CONCLUSION: S-100B protein has a reliable value in diagnosis and prognostic after severe head injury.
, 百拇医药
    PAGE:223-225

    Clinical study of cerebral oxygen utilization coefficients in patients with severe head injury

    Tian Hui, Wu Tie-jun, Zhang Lian-qun, Tian Suo-chen, Qu Ai-jun, Cai Xiu-hua

    ICU,Liaocheng People's Hospital, Liaocheng 252000, Shandong, China

    OBJECTIVE: To investigate the relationship in cerebral oxygen utilization coefficients (O.2UCc) in patients with acute severe head injury and illness prognosis. METHODS: Forty patients with acute severe head injury were studied, and 40 patients with light head injury were used as control. Through blood analysis, the changes in oxygen saturation of carotid blood(SaO2), oxygen saturation of jugular blood (SjO2), cerebral arteriovenous difference of oxygen saturation〔S(a-j)O2〕, O.2UCc were observed. Furthermore, the relationship of these patients' condition and prognosis was analyzed. RESULTS: There was no significant change between the test group and control group in SaO2. In test group, SjO2 increased and O.2 UCc decreased, there was an obvious difference between two groups (both P<0.01). In test group, 26 died and 14 lived. There was no significant difference between died and lived patients in SaO2. SjO2 significantly increased and O.2 UCc obviously decreased in died patients in comparison with those of the lived patients (both P<0.01). CONCLUSION: Cerebral oxygen metabolism dynamics obstacle frequently was accompanied with acute severe head injury. The high SjO2 and low O.2 UCc are main symptoms with O.2 UCc<11percent hinting a bad prognosis.
, 百拇医药
    PAGE:226-228

    Pathomorphological changes in abdominal viscerae in dogs subjected to underwater blast wave injury

    Yang Zhi-huan, Zhu Pei-fang, Jiang Jian-xin, Wang Zheng-guo, Yin Zhi-yong, Li Xiao-yan, Ning Xin, Zhou Ji-hong, Feng Gang, Liu Da-wei

    Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China

    OBJECTIVE: To explore the pathomorphological changes in abdominal viscerae injuries produced by underwater blast waves. METHODS: Sixty-one adult mongrel dogs were used in this study. Underwater explosions in different intensity were produced by detonating 200 g, 500 g and 1 000 g TNT, respectively. The physical parameters of blast wave were measured by PCB dynamic pressure transducers specially designed for underwater explosion. The pathomorphological changes in abdominal viscerae were observed at 6 hours after injury. RESULTS: The physical features of underwater blast wave were characterized by high peak pressure, short positive action duration, and higher intensity of impulse. The pathomorphological observation revealed high incidence of injuries of gastrointestinal tract (62.30 percent), manifesting mainly various degrees of subserosal and submucous bleeding in gastrointestinal tract. Rupture of seromuscular layer, subserosal hematoma, and even, perforations of gastrointestinal tract occurred in some animals. Injuries of the liver, spleen, pancreas and other parenchymatous organs injuries, such as subcapsular bleeding, hematoma, and ruptures, appeared with low incidence. No obvious injuries were found in the gallbladder or urinary bladder and other fluid containing organs. CONCLUSION: Underwater blast wave can induce injuries to many abdominal viscerae. Gastrointestinal tract injuries, occurring in high incidence are usually severe, and they should be given early treatment in underwater blast injuries.
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    PAGE:229-231

    Analysis of acute respiratory dysfunction as a risk factor of multiple injuries

    Hao Jiang, Lei Ming, Zhang Yin, Weng Qi, Yang Ming-hao, Wu Sheng-ping.Emergency Department, Kunming General Hospital of Chengdu Military Command, Kunming 650032, Yunnan, China

    OBJECTIVE: To study the relationship between multiple injuries and acute respiratory dysfunction (ARD). METHODS: One hundred and ten patients with multiple injuries admitted during the last 6 years were retrospectively analyzed. With ARD as the dependent variable and other 11 factors as independent variables, all analysis was done statistically on computer to identify the complication of ARD as a risk factor. RESULTS: Multivariable and single argument analysis showed systemic inflammatory response syndrome (SIRS), pulmonary contusion, co-existing lung disease as chronic obstructive pulmonary disease (COPD) and pneumonia, moderate hemothorax and pneumothorax, duration of shock over 12 hours, age over 55 years, injury severity score(ISS)>24 were high risk factors. CONCLUSION: Patients with multiple injuries with high risk factors should be kept under closer observation in order to prevent ARD and multiple organ dysfunction syndromes (MODS).
, 百拇医药
    PAGE:231

    Comprehension of 3 cases of healing rupture of heart caused by stab wound in abdomen

    Yu Jian-qi, Li Jie, Sheng Qi-mei, Li Ji-ye, Lu Jia-qi

    Department of cardiothoracic surgery, 304th hospital of PLA, Beijing 100037, China

    PAGE:232-234

    Protective effect of continuous veno-venous hemofiltration on tissue and organ damage in patients with severe acute pancreatitis
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    Yang Zhao-hui, Yang Jun, Wang Yong-jun

    The General Hospital of Tianfu Coal Bureau, Chongqing 400704, China

    OBJECTIVE: To explore the protective effect of continuous veno-venous hemofiltration (CVVH) on tissue and organ damage induced by severe acute pancreatitis (SAP). METHODS: Thirty-seven SAP patients were randomly divided into CVVH group (n=22) and control group (n=15). Patients in control group were treated with conventional therapy, while patients in CVVH group were treated with conventional therapy combined with CVVH. Serum amylase (AMS) and lipase (Lip), the plasma levels of endotoxin, tumor necrosis factor-α(TNF-α), interleukin-1β(IL-1β), and C-reactive protein (CRP), and faecal occult blood test and blood serum leukocyte were determined. Functions of brain, kidney, liver, heart and lung were observed. RESULTS: The treatment effect was better in CVVH group than that in normal group. The mortality rate was lower and the number of hospitalization day was decreased in CVVH group than those in normal group, they were 18.2 percent vs. 33.3 percent and (18.3±5.7) days vs. (27.5±8.6) days. CONCLUSION: CVVH has a significant protective effect against tissue and organ damage induced by SAP.
, 百拇医药
    PAGE:235-238

    Investigation on risk factors of prolonged mechanical ventilation after cardiopulmonary bypass

    Chen Bai-cheng, Xiao Ying-bin, Qian Gui-sheng, Chen Lin, Zhong Qian-jin, Wang Xue-feng, Wang Hui-chun, Liu Xiao-li, Zhu Xue-min.

    Department of Cardiovascular Surgery, Xinqiao Hospital, the Second Affiliated Hospital of the Third Military Medical University, Chongqing 400037, China
, 百拇医药
    OBJECTIVE: To analyze the risk factors of prolonged mechanical ventilation (PMV) after cardiopulmonary, and to improve the management for the patients underwent respiratory complications. METHODS: From January 1995 to August 2003, there occurred 50 cases of patients in our ICU. The clinical data of 50 cases of patients in our ICU who undergoing open heart surgery was reviewed retrospectively, and the multivariate liner regress analysis model was used to evaluate the influence of the variables. RESULTS: The age of the patients underwent PMV ranged from 14 to 65 years old, body weight 28 to 80 kg, 28 cases of the patients were male, and 22 female. Mean cardiopulmonary bypass (CPB) time was (156.38±52.02) minutes. Mean mechanical ventilation time was (62.86±22.55) hours. The mortality was 18.0 percent. Compared to the contrast, the patients in prolonged ventilation groups were in higher NYHA class, underwent longer period of CPB time and cross-clamping time (P<0.001). The postoperative arterial partial pressure of oxygen (PaO2) and PaO2/FiO2 were much lower, the alveolar-arterial oxygen pressure gradient and the intrapulmonary shunt (Qs/Qt) were higher (all P<0.001). There was no significant difference in pulmonary dynamic compliance between the two groups. The postoperative drainage was much more, and the myocardial enzymes were in higher level in prolonged ventilation groups (both P<0.001). The incidence of postoperative complications was higher (P<0.001). Multivariate liner regress analysis showed that the duration of mechanical ventilation was related with the preoperative cardiac function, CPB time, PaO2/FiO2, the level of postoperative myocardial enzyme, and the quantity of postoperative drainage. CONCLUSION: This study shows preoperative cardiac function, CPB time, PaO2/FiO2, the level of postoperative myocardial enzyme and the quantity of postoperative drainage are risk factors of PMV.
, 百拇医药
    PAGE:238

    Effect of Naloxone on acute alcohol posieness

    Zhou Ming-hua, Lai Hai-bo

    The People’s Hospital, Beihai 536000, Guangxi, China

    PAGE:239-241

    Clinical study on value of severity of patient with coronary artery disease evaluated with the thrombosis in myocardial infarction risk score

    Zheng Xiao-ying, Meng Xin-ke, Li Wen-guang, Yang Jing, Wei Gang, Fang Rui
, 百拇医药
    Emergency Department of Shenzhen Second People's Hospital, Shenzhen 518035, Guangdong, China

    OBJECTIVE: To explore the value of severity evaluating and outcome predicting on coronary artery disease (CAD) patients scored with the thrombosis in myocardial infarction (TIMI) risk score. METHODS: All of 126 patients with CAD were enrolled in study. TIMI risk score and coronary artery angiographic in them were performed respectively. Correlativity between TIMI risk score and clinical type of CAD, narrow severity, pathological changes limits and character of coronary artery were analyzed. Difference of scores of TIMI, narrow severity, pathological changes limits and character of coronary artery were compared among stable angina (SA), unstable angina (UA), un-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI) respectively. RESULTS: TIMI risk score significantly correlated with clinical type of CAD score, narrow severity score, pathological changes limits and character scores of coronary artery respectively(r=0.607 for narrow severity score, 0.569 for pathological changes limits score, 0.367 for pathological changes character score, all P<0.05). TIMI risk score increased company with severity of coronary artery pathological changes advancing. Significantly differences were found when TIMI risk scores were compared between SA and UA, NSTEMI and STEMI respectively as well as narrow severity scores (all P<0.05). Same results were found between UA and NSTEMI, STEMI respectively (all P<0.05). There had no significantly difference among pathological changes limits scores of SA, UA, NSTEMI, STEMI (all P>0.05). Significantly difference was found when pathological changes character scores were compared between SA and UA, NSTEMI, STEMI respectively as well as narrow severity scores (P<0.05), but contrary result were found between UA and NSTEMI, STEMI respectively (P>0.05). CONCLUSION: TIMI risk score not only could be used to predict the possibility of heart accident, but also could be used to evaluate clinical type of CAD, narrow severity, pathological changes limits and character of coronary artery in CAD patient.
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    PAGE:242-243

    Study on TGF-β1 in the serum of patients with acute cerebral infarction

    Yang Qiao-lian, Liu Dan, Gong Bo, Zhang Jun-qing, Zhang Hong-yu, Zhao Li-ying, Du Xiu-qing

    Department of Neurology, the First Affiliated Hospital of Baotou Medical College, Neimenggolia 014010, China

    PAGE:244-245

    Experimental observation on change of Mg2+ and water contents in ballistic trajectories after craniocerebral gunshot wound in canines
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    Feng Ya-ping, Zhang Xiang, Bai Xiu-song, Wu Ge, Fei Zhou, Wang Xi-ling

    Department of Neurosurgery, Kunming General Hospital of Chengdu Military Command, Chengdu 650032, Sichuan, China

    PAGE:245

    Influence of Militone or hemodynamic in patients with congestive heart injury

    Ma Zhi-min, Li Qin-ling, Cui Rong-en, Wang Ping-jing

    The General Hospital of Jingmei Group, Beijing 102300, China
, 百拇医药
    PAGE:246-247

    Effect of Enama on Acidosis in Newborn Pat with Hypoxic-Ischemic by Enema

    Yao Li, Fu Zhong-qiu, Yao Wei-guang

    The second Hospital of Haerbin Medical University, Heilongjiang 150086, China

    PAGE:247-248

    Dynamic change of blood sugar level after cerebral stroke

    Zhang Feng, Xu Guan-jie
, 百拇医药
    Department of Nuclear Medicine, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China

    PAGE:249-250

    The clinical study of nimodiping used in hypertensive intracerebral hemorrhage after operation

    Zhang Jun, Zhang Jian-jun, Gao Guo-liang, Dong Wei-feng, Gu Shui-jun, Xuan Hong-fei, Xie Ren-long, Si Yun

    Neurosurg Xiaoshan NO.1 people’s Hospital, Hangzhou 311201, China
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    PAGE:251-252

    The state and outcomes evaluated by the score of hypertensive cerebral hemorrhage

    Ma Dong-zhou, Yang Ling, Xi Zhen-dong, Wang Hong-bin

    Department of neurosurgery, Affiliated Hospital, Hebei Engineering College, Handan 056002, Heibei, China

    PAGE:252

    Observation of healing effect of 71 patients with hypertension and cerebral hemorrhage treated with minimally invasive clearance operation
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    Chen Zi-qing, Zhuang Yao-ming, Huang Pei-kun

    AnXian Hospital, Fujian 362100, China

    PAGE:253-256

    Review about research progress of acidic fibroblast factor and its receptor

    Weng Li-xin, Li Xiu-xia, Fu Xiao-bing

    Key Research Laboratory of Wound Repair, Burns Institute, 304 th Hospital of PLA, Beijing 100037, China, http://www.100md.com