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多潘立酮对正常人胆囊排空的影响
http://www.100md.com 1996年5月15日 《世界华人消化杂志》 1996年第5期
胆囊排空;多潘立酮,项目负责人,Effectsofdomperidoneongallbladderemptyinginnormalpersons,,Abstract,AIMS,METHODS,RESULTS,CONCLUSIONS,Subjectheadings,摘要,目的,方法,结果,结论,主题词,1,对象和方法,1.1对象,1.2,方法,1.3,实验步骤
     解放军第451医院内五科陕西省西安市 710054

    项目负责人
陈仕珠,710054,陕西省西安市,解放军第451医院内五科 收搞日期 1995-04-12

    Effects of domperidone on gallbladder emptying in normal persons

    Shi-Zhu Chen, Xu-Chun Chen and Xiao-LingGuo

    Fifth Department of Internal Medicine, Chinese PLA 451 Hospital, Xi'an 710054 China

    Abstract

    AIMS To investigate the effects of domperidone(Dom) on gallbladder(GB) emptying in normal persons.

    METHODS The effects of Dom on GB emptying in 18 normal subjects were studied by ultrasonography according to randomized, double-blind and self-controlled protocol.

    RESULTS GB emptying was slow after oral Dom. GB ejection fraction(GBEF) was significantly decreased at postprandial 30min after oral 20mg Dom(P<0.05), and the decrease was more significant 60min after the meal (P<0.01). A marked difference was found between 10mg Dom and 20mg Dom on GBEF after the meal. No significant difference was found between 10mg Dom and without Dom(P>0.05) although 10mg Dom made GBEF decreased. The speed of GB emptying was slower, and the maximum GBEF was significantly less in 20mg Dom than in 10mg Dom and no Dom after the meal(P<0.01). ......

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