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实验性肝硬变形成过程中层粘连蛋白的动态变化
http://www.100md.com 1997年1月15日 《世界华人消化杂志》 1997年第1期
肝硬化;层粘连蛋白,肝;结蛋白,肝,项目负责人:,Changesoflamininintheliverofratswithexperimentalcirrhosis*,Sponsoredby,Correspondenceto,Received,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘要,目的,方法,结果
     1山西医科大学病理教研室 山西省太原市 030001

    2山西医科大学肝病研究所

    项目负责人:龚爱玉

    Changes of laminin in the liver of rats with experimental cirrhosis*

    Ai-Yu Gong1, Xue-Hui Ma2, Rei-Ling Xu2, Lei Yin2, Xian-Ming Chen2, Yuan-Chang Zhao2 and De-Wu Han2

    1
Department of Pathology, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.

    2Institute of Hepatology, Shanxi Medical University.

    Dr. GONG Ai-Yu, born in 1964-09-12 in Puqi City, Hubei Province, graduating from Shanxi Medical University as postgraduate in 1993, having 5 papers published.

    Tel:0086-351-2021511 ext 283, Fax:0086-351-2024239

    Sponsored by the Youth Natural Scientific Foundation of Shanxi P rovince (No. 93017).

    Correspondence to Dr. Ai-Yu Gong.

    Received 22nd August 1996.

    Abstract

    AIM
To reveal the changes of laminin and desmin positive cells and their correlations in rat liver with experimental cirrhosis.

    METHODS Experimental cirrhosis in rats was induced by carbon te trachloride and dietetic injury. Rats were sacrificed at different stages during the development of liver fibrosis. The contents of collagen in the liver were determined and the changes of laminin and desmin positive cells in liver were obs erved by immunohistochemical and electron-microscopic technique. Normal rats we re used as the controls. ......

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