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编号:10695299
胃安素治疗慢性萎缩性胃炎的临床与实验研究
http://www.100md.com 1998年2月15日 《世界华人消化杂志》 1998年第2期
胃炎,萎缩性,中医药疗法;补益脾肾;地黄,治疗应用;黄芪,治疗应用;白术,治疗应用,项目负责人,Correspondenceto,ClinicalandexperimentalstudyofWeiAnSuinchronicatrophicgastritis,,Abstract,,AIM,METHODS,RESULTS,CONCLUSION
     1北京市中医研究所 1000232北京中医医院

    危北海,男,1931-06-15生,江西省南城县人,汉族. 1954年第七军医大学毕业,北京市中医研究所主任医师,主要从事中医脾胃学说和消化系统疾病的中医诊治研究,先后发表论文116篇,获得卫生部、北京市科委和北京市卫生局、中医管理局科技成果进步奖24项,享受政府特殊技术津贴.

    项目负责人 危北海,100010,北京市中医研究所,北京市美术馆后街23号.

    Correspondence to Bei-Hai Wei, Beijing Institute of Traditional Chinese Medicine, 23 Meishuguan Houjie, Beijing 100010, China

    Tel. +86·10·64011391

    收稿日期 1997-09-12 接收日期 1997-11-15

    Clinical and experimental study of Wei An Su in chronic atrophic gastritis

    Bei-Hai Wei1, Zhan-Hai Zhang2, Li-Cai Yang1, Jin-Sheng Liu1, Min Zhao2, Rong-Lai Zhao1 and Qian-Gou Li2

    1Beijing Institute of Traditional Chinese Medicine, Beijing 100010, China

    2Beijing Hospital of Traditional Chinese Medicine

    
Abstract

    AIM To evaluate the therapeutic effect of Wei An Su Capsule (WASC) in the treatment of chronic atrophic gastritis (CAG).

    METHODS Sixty cases of CAG diagnosed endoscopically and histopathologically were divided into two groups. Group A (31 cases) was treated with WASC, and group B (29 cases) with Wei Mei Su Tablet. Gastric mucosal histomorphology was observed under endoscope, light and electron microscope. The experimental chronic atrophic gastritis model with Spleen and Kidney deficiency in male Wistar rats was established successfully by the method of multi-elementary damages, such as active immunity, sodium deoxychlate and cold bile and irregular feeding were administered, the preventiven experiment was carried out simultareously. On the 50th day, all animals were killed, and gastric mucosa were observed. ......

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