丙型肝炎患者血清中高变区1(HVR1)抗体的检测与分析
肝炎,丙型,免疫学;抗体,病毒,分析;RNA,病毒,分析;预后,项目负责人,Correspondenceto,Detectionofantibodiesagainsthypervariableregion1inserafrompatientswithhepatitisC,,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subje
第三军医大学西南医院全军传染病专科中心 重庆市 400038宋志强,男,1972-02-19生,河南省上蔡县人,汉族,1995年第三军医大学毕业,学士,1996年第三军医大学硕士,主要从事丙型肝炎发病机制和防治的研究,发表论文或综述8篇.
项目负责人 宋志强,400038,重庆市,第三军医大学西南医院全军传染病专科中心.
Correspondence to Dr. Zhi-Qiang Song, Centre for Infectious Diseases of Chinese PLA, Southwest Hospital,Third Military Medical University, Chongqing 400038, China
Tel. +86·23·68754217, Fax.+86·23·68754475
Email.Songzq@263.net http://songzq.163.net
收稿日期 1999-04-15 接收日期 1999-06-18
Detection of antibodies against hypervariable region 1 in sera from patients with hepatitis C
Zhi-Qiang Song, Fei Hao, Juan Zhang and Chang-Hai Gu
Centre for Infectious Diseases of Chinese PLA, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
Abstract
AIM To investigate the antibody response directed to hypervariable region 1(HVR1) of hepatitis C virus (HCV) in hepatitis C patients and to evalulate the relationship between such antibody response and prognosis of hepatitis C.
METHODS An ELISA using synthetic peptide containing HVR1 sequences was used for detection of anti_HVR1 in 45 sera cases. HCV RNA in above sera were also examined by reverse transcription polymerase chain reaction (RT-PCR). ......
您现在查看是摘要页,全文长 11064 字符。