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编号:10696285
丙型肝炎患者血清中高变区1(HVR1)抗体的检测与分析
http://www.100md.com 1999年8月15日 《世界华人消化杂志》 1999年第8期
肝炎,丙型,免疫学;抗体,病毒,分析;RNA,病毒,分析;预后,项目负责人,Correspondenceto,Detectionofantibodiesagainsthypervariableregion1inserafrompatientswithhepatitisC,,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subje
     第三军医大学西南医院全军传染病专科中心 重庆市 400038

    宋志强,男,1972-02-19生,河南省上蔡县人,汉族,1995年第三军医大学毕业,学士,1996年第三军医大学硕士,主要从事丙型肝炎发病机制和防治的研究,发表论文或综述8篇.

    项目负责人
宋志强,400038,重庆市,第三军医大学西南医院全军传染病专科中心.

    Correspondence to
Dr. Zhi-Qiang Song, Centre for Infectious Diseases of Chinese PLA, Southwest Hospital,Third Military Medical University, Chongqing 400038, China

    Tel. +86·23·68754217, Fax.+86·23·68754475

    Email.Songzq@263.net http://songzq.163.net

    收稿日期 1999-04-15 接收日期 1999-06-18

    Detection of antibodies against hypervariable region 1 in sera from patients with hepatitis C

    Zhi-Qiang Song, Fei Hao, Juan Zhang and Chang-Hai Gu

    Centre for Infectious Diseases of Chinese PLA, Southwest Hospital, Third Military Medical University, Chongqing 400038, China

    


    Abstract

    AIM To investigate the antibody response directed to hypervariable region 1(HVR1) of hepatitis C virus (HCV) in hepatitis C patients and to evalulate the relationship between such antibody response and prognosis of hepatitis C.

    METHODS An ELISA using synthetic peptide containing HVR1 sequences was used for detection of anti_HVR1 in 45 sera cases. HCV RNA in above sera were also examined by reverse transcription polymerase chain reaction (RT-PCR). ......

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