幽门螺杆菌感染对胃病细胞动力学的影响
螺杆菌感染;胃疾病;细胞动力学;胃肿瘤,项目负责人,Correspondenceto,EffectofHpinfectionongastricepithelialcellkineticsinstomachdiseases,,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘要,目的,方法,结果,结论
福建省立医院 1消化研究室 2病理科 福建省福州市 350001卢世云，男，1970-08-10生，江西省万载县人，汉族. 1991年九江医专医疗系毕业，1999年福建医科大学内科学硕士，主要从事幽门螺杆菌感染的基础与临床研究.
项目负责人 卢世云，350001，福建省福州市东街134号，福建省立医院消化研究室.
Correspondence to Shi-Yun Lu, Gastroenterology Research Unit of Fujian Provincial Hospital, Fuzhou 350001, Fujian Province, China
Tel. +86·591·7557768 Ext.9035
Email. a 9035@pub2.fz.fj.cn
收稿日期 1999-04-15 接收日期 1999-06-21
Effect of Hp infection on gastric epithelial cell kinetics in stomach diseases
Shi-Yun Lu, Xiu-Zhen Pan, Xiao-Wei Peng and Zuo-Lin Shi
Gastroenterology Research Unit of Fujian Provincial Hospital, Fuzhou 350001, Fujian Province, China
Abstract
AIM To investigate the effect of Helicobacter pylori (Hp) infection on the gastric epithelial cell kinetics in the progression from normal mucosa to gastric carcinoma and the mechanisms of Hp causing gastric maligancy.
METHODS By using immunohistochemical technique, the Ki-67 labelling index (LI%) was used to assess the gastric antral epithelial cell proliferation in bioptic gastric mucosa specimens of normal gastric mucosa dyspeptic subjects (NS, n=14) and five groups of patients (chronic superficial gastritis, CSG, n=56; chronic atrophic gastritis, CAG, n=20; chronic atrophic gastritis with intestinal metaplasia, CAGIM, n=16; dysplasia, Dys, n=18; gastric cancer, GC, n=17). Each was comprised of Hp positive and negative patients. ......
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