中药胃炎消治疗大鼠慢性萎缩性胃炎的病理研究
胃炎消,治疗应用;胃炎，萎缩性,中医药疗法,国家“八五”攻关项目，,No.85-919-01-01,项目负责人,Correspondenceto,PathologicstudiesofChinesedrugWeiyanxiaoonexperimentalchronicatrophicgastritisinrats,Abstract,A
广州中医药大学 1脾胃研究所 2基础医学院 广东省广州市 510405王汝俊，男，1950-09-09生，广东省电白县人，汉族. 1988年广州中医药大学中西医结合基础专业毕业，医学硕士，副教授，广州中医药大学脾胃研究所中药药理室主任. 主要从事中药胃肠道药理研究，发表专业论文30篇.
国家“八五”攻关项目，No.85-919-01-01
项目负责人 王汝俊，510405，广东省广州市，广州中医药大学脾胃研究所.
Piwei Institute, Guangzhou University of Traditional Chinese Medinine, Guangzhou 510405, Guangdong Province, China
Correspondence to Ru-Jun Wang, Piwei Institute, Guangzhou University of Traditional Chinese Medinine, Guangzhou 510405, Guangdong Province, China
Tel. 0086-20-86591233 Ext. 2555
Email. pwyaol@gzhtcm.edu.cn
收稿日期 1999-11-25 接收日期 2000-01-12
Pathologic studies of Chinese drug Weiyanxiao on experimental chronic atrophic gastritis in rats
Ru-Jun Wang, Qun Du, Ting-Yin Shao, Ting-Ji Zhong, Yan-Li Wu and Jian-Hua Wang
Abstract
AIM To study the effects of Weiyanxiao (WYX) on experimental chronic atrophic gastritis(CAG) in rats.
METHODS CAG model in rats was made using complex METHODS of active immunization combined with oral administration of sodium deoxycholate and hot water for 90d, followed by the treatment with administration of WYX orally in the dosages of 12.3g/kg and 24.6g/kg (5 and 10 times according to the clinic dosages) for 60d. Then the acidity of gastric juice was measured using acid-base balance. The histopathological changes including the depth of mucosa, muscular layers, gastric pit and length of gastric glands were measured with micrometer under optical microscope. The degrees of inflammation in gastric mucosa were evaluated with score according to the numbers of inflammatory cells. ......
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