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贲门失弛缓症犬动物模型的建立
http://www.100md.com 2002年11月15日 《世界华人消化杂志》 2002年第11期
向正国,张忠兵,朱梁,张兴荣,项目负责人,Establishmentofachalasiamodelindogs,Correspondenceto:,Received,Accepted,Abstract,摘要,目的,:,方法,结果,结论,0,引言,1,材料和方法,1.1,材料,1.2,统计学处理,2,2.1BAC,对LES,压力的影响,2.2,两组犬NOS
     向正国,中国人民解放军第101医院消化内科 江苏省无锡市 214044

    张忠兵,朱梁,张兴荣,中国人民解放军第二军医大学附属长征医院消化内科 上海市 200433

    向正国,男,1966-01-15生,重庆合川人,汉族,1988年第三军医大学本科毕业,2000年第二军医大学硕士研究生毕业,主治医师,主要从事胃肠运动性疾病的研究.

    项目负责人 向正国,214044,江苏省无锡市,中国人民解放军第101医院消化内科.

    收稿日期 200206-29 接受日期 2002-07-15

    Establishment of achalasia modelin dogs

    
Zheng-Guo Xiang,Zhong-Bing Zhang , Liang Zhu,Xin-Rong Zhang

    Zheng-Guo Xiang, Department of Gastroenterology, 101 Hospital of PLA, Wuxi 214044, Jingsu Province, China

    Zhong-Bing Zhang, Liang Zhu, Xin-Rong Zhang, Division of Gastroenterology, Changzheng Hospital, the Second Military Medical College, Shanghai 200043, China

    Correspondence to: Zheng-Guo Xiang, Department of Gastroenterology, 101 Hospital of PLA, Wuxi 214044, Jingsu Province, China.

    Received 2002-06-29 Accepted 2002-07-15

    AbstractAIM:To develop an achalasia model in dog.

    METHODS:Benzyl-dimethyltetradecylammonium chloride (BAC)(4 mmol/L, 12 mL) was endoscopically injected circumferentially into the lower esophageal sphincter(LES) in 10 adult dogs and saline injection in 10 adult dogs as control. Six weeks after injection, manometry was performed, and the frequency and degree of relaxation were recorded. The clinical symptoms and esophageal barium test were observed. By means of immunochemical method, NOS-positive myoenteric ganglion cells were stained. ......

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