大肠腺瘤及癌组织HIF-1a的表达与凋亡增生的关系
程胜平,刘南植,钱颉,项目负责人,:,ExpressionofHIF-1aanditsrelationswithapoptosisandproliferationincolorectalneoplasm,Abstract,摘要,目的,方法,结果,结论,0,引言,1,材料和方法,1.1材料,1.2方法,统计学处理,2,结果,2.1HIF-1
程胜平,刘南植, 钱颉,华中科技大学同济医学院附属同济医院消化内科 湖北省武汉市 430030程胜平,男, 1972-04-12生,湖北省武汉市人,汉族, 2002级华中科技大学同济医学院硕士生,主要从事消化道肿瘤的基础及临床研究.
项目负责人:程胜平,430030, 湖北省武汉市,华中科技大学同济医学院附属同济医院消化内科. sheng_ping2004@sina.com
电话:027-83663208
收稿日期:2004-10-18 接受日期:2004-11-27
Expression of HIF-1aand its relations with apoptosis and proliferation in colorectal neoplasm
Sheng-Ping Cheng, Nan-Zhi Liu, Jie Qian
Sheng-Ping Cheng, Nan-Zhi Liu, Jie Qian, Department of Gastroenterology,Tongji Hospital, Tongji Medical College, Huazhong University of Scienceand Technology, Wuhan 430030, Hubei Province, China
Correspondence to: Sheng-Ping Cheng, Department of Gastroenterology,Tongji Hospital, Tongji Medical College, Huazhong University of Scienceand Technology, Wuhan 430030, Hubei Province, China.
Received: 2004-10-18 Accepted:2004-11-27
AbstractAIM: To study the expression of HIF-1aand its relationship with apoptosis and proliferation in human colorectalneoplasm
METHODS: Expression of HIF-1a,Bcl-2, Bax and PCNA was detected in normal colorectal tissue (n =13), colorectal adenoma (n = 26) and adenocarcinoma (n = 50)by the immunohistochemical method respectively. ......
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