【摘要】 目的 探讨原发性颅内恶性淋巴瘤的发病机制、临床表现、诊断治疗及预后。方法 回顾性分析经病理检查证实的9例恶性淋巴瘤。结果 该肿瘤少见，多发生于幕上，临床上无特征性表现，术前多被误诊。采用手术切除，放疗及化疗即综合治疗者中位生存期18个月。结论 原发性颅内恶性淋巴瘤术前难以确诊、预后差。手术应以保留患者重要神经功能为前提，对于术中不能全切的残瘤及肿瘤直径<3cm者，可行γ-刀治疗。强调手术与放、化疗结合的综合治疗。

    Primary intracranial malignant lymphoma

    Zhao Haikang，Xie Changhou，Zhang Xiaodong，et al.

    Dept of Neurosurgery，the First Hospital of Xi’an Jiaotong University，Xi’an，Shaanxi710061.

    【Abstract】 Objective To explore the mechanism，clinical manifestation，diagnosis，treatment and prognosis of primary intracranial malignant lymphoma(PIML).Methods 9cases with PIML who were proved by histopathology were retrospectively analyzed.Results PIML is rare in clinic，most of them are located supratentorial，which have no special clinical manifestation and are misdiagnosis usually.The median survival time is18months of cases who had been treated with excision combined irradiation and chemotherapy.Conclusion PIML is difficult to be diagnosed preˉoperation ......