【摘要】 目的 评价粪便幽门螺杆菌抗原(HpSA)试验在诊断儿童幽门螺杆菌感染中的应用价值。方法 用HpSA试验检测有消化道症状的58例患儿HpSA，并同时进行 14 C标记的尿素呼气试验( 14 C-UBT)，以 14 C-UBT作为金标准，对HpSA试验进行方法学评价。结果 HpSA试验对Hp感染诊断的敏感性为94.6%、特异性为95.2%、准确性为94.8%、阳性预期值为97.2%、阴性预期值为90.0%。应用HpSA试验检测了1015名健康学生HpSA，阳性率为20.0%。结论 HpSA试验是一种诊断儿童幽门螺杆菌感染的简便、易行、准确性高的非侵入性方法。

    关键词 幽门螺旋杆菌 粪便 抗原 儿童

    Applicative study of stool HpSA detecting for Helicobacter pylori infection screening in children

    Zhang Jian，Xie guoqiang，Zhou Ying

    Wuxi Children’Hospital，Jiangsu214002.

    【Abstract】 Objective To evaluate the applicative value of stool HpSA(Helicobacter pylori antigen)detecting in the diagnosis of Helicobacter pylori(Hp)infection in children.Methods Detecting HpSA among58children with digesˉtive tract symptoms by HpSA test. 14 C-urea breath test( 14 C-UBT)as golden standard was carried out simultaneously to evaluate the methology of HpSA test.Results In the diagnosis of Hp infection ......