【摘要】 目的 研究百部乳膏对动物皮肤的毒性作用。方法 利用健康SD大鼠进行皮肤急性毒性试验，用健康白兔进行皮肤刺激性试验;用健康豚鼠进行皮肤过敏试验。结果 百部乳膏对大鼠完整皮肤及破损皮肤均无急性毒性反应，对白兔完整皮肤和破损皮肤无刺激性，对豚鼠完整皮肤无致敏作用。结论 百部用于治疗蠕形螨病时是较安全的。

    Cui Chunquan，Shen Chenghua，Zheng Shanzi，et al.

    Department of Human Parasitology，College of Medicine，Yanbian University，Yanji133000.

    【Abstract】 Objective To study toxicity of Stemona sessilifolia cream on the skin of animals.Methods A experiment of acute cutaneous toxicity was performed on the skin of healthy rats;Cutaneous stimulation was performed in the skin of healthy rabbit;Cutaneous hypersensitivity was performed in healthy guinea pig.Results The Stemona sessilifolia cream had no acute toxicity，no cutaneous stimulation and no hypersensitive effects for the intact or damˉaged skin in rats，rabbits and guinnea pigs respectively.Conclusion It is safe for Stemona sessilifolia to treat the pediculosis and demodicidosis.

    Key words Stemona sessilifolia administration skin toxicity test rats

    百部 [1] 为百部科多年生草本植物 ......