【摘要】 目的 探讨血清心脏肌钙蛋白Ⅰ(cTnI)水平对不稳定心绞痛(UAP)患者近期预后的判定价值。方法 对50例健康人、20例稳定心绞痛患者和45例UAP患者分别进行cTnI和肌酸磷酸激酶同工酶(CK-MB)检测，并对UAP患者进行随访，观察心脏事件发生率。结果 45例UAP患者中21例(46.7%)cTnI≥0.77ug/L，cTnI升高的UAP患者中，16例(76.2%)为BraunwaldⅢ级，显著高于cTnI正常患者(6例，25.0%，P<0.01)。住院期间心脏事件发生率，cTnI升高组(13/21，61.9%)显著高于cTnI正常组(5/24，20.8%，P<0.01)。血清cTnI水平对于预测心脏事件，敏感性61.9%，特异性79.2%，阳性预测价值72.2%，阴性预测价值59.3%，准确性71.1%。结论 cTnI是反映心肌损伤敏感性和特异性均较好的生化指标，对识别高危UAP患者，判断UAP预后有一定临床价值。

    关键词 心脏肌钙蛋白Ⅰ 不稳定心绞痛 预后

    The short-term prognostic value of serum cardiac troponinⅠin patients with unstable angina

    Li Jing，Xu Zhimin，Wang Tie，et al.

    Heart Center，Beijing Chaoyang Hospital，Capital University of Medical Sciences，Beijing100020.

    【Abstract】 Objective To evaluate the short-term prognostic value of serum cardiac toponin I(cTnI)in paˉtients with unstable angina(UAP).Methods Blood samples from45patients with UAP，20patients with stable angina(SAP)and50healthy persons were collected serially and detected cTnI and CK-MB respectively.Coronary angiography was performed in all UAP patients and all UAP patients were followed-up during hospitalization.Results (1)of45UAP patients ......