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编号:10573845
豆楮方对人肝癌细胞株HepG 2 体外抑制作用的实验研究
http://www.100md.com 《中华现代中西医杂志》 2004年第12期
豆楮方,豆楮方,人肝癌细胞株HepG,2,实验研究,豆楮方对人肝癌细胞株HepG2体外抑制作用的实验研究,1材料与方法,2结果,3讨论,参考文献
     【摘要】 目的 研究豆楮方对人肝癌细胞株HepG 2 的生长增殖抑制作用,从分子生物学角度探讨其抗癌作用机制。方法 文献法制备豆楮方含药血清,用MTT法观察药物作用24h、48h后细胞的增殖情况。结果 豆楮方含药血清在体外对人肝癌细胞株HepG 2 有显著的抑制作用,作用24h的最高抑瘤率为91.48%,作用48h的最高抑瘤率为90.31%,抑瘤效果优于5-FU。结论 豆楮方具有抗肝癌作用。

    关键词 豆楮方 人肝癌细胞株HepG 2 实验研究

    The Experimental Research on the Inhibiting action of Dou-Chu Formula on the Proliferation of HepG 2 cell line in vitro

    Peng Haiyan,Zhang Xiaochun,Zhang Yonghong,et al.

    The First Clinical Medical College,Traditional Chinese Medicine University of Nanjing,Nanjing210029.

    【Abstract】 Objective To observe the inhibiting action of Dou-Chu formula on the proliferation of HepG 2 cell line in vitro,so as to discuss its anticancer mechanisms.Methods Obtain pharmaceutic serum of the rabbit after feeding itwith Dou-Chu formula for5days.HepG 2 cell line was treated with the pharmaceutic serum at different conˉcentrations for24h and48h respectively.The inhibiting rate of cells was observed byMTT.Results The proliferation of HepG 2 cells was obviously inhibited after being treated with Dou-Chu formula.The best effect for24h was91.48%and that of48h was90.3%.Conclusion Dou-Chu formula has anticancer function. ......

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