【摘要】 目的 探讨肝炎患者外周血T淋巴细胞AgNORs含量及NK细胞活性变化。方法对198例肝炎患者及30例正常人进行T淋巴细胞AgNORs NK细胞活性及HBV-DNA含量检测。结果乙肝患者随着病情的加重，T淋巴细胞AgNORs含量逐渐降低，急性肝炎患者NK细胞活性与轻度慢性肝炎之间比较无差异外，与其他各型肝炎比较，差异均有非常显著性(P<0.01)，各型肝炎间HBV-DNA含量差异无显著性。肝炎患者体内HBV-DNA含量对T淋巴细胞AgNORs含量、NK细胞活性无影响。结论 T淋巴细胞AgNORs含量及NK细胞活性在肝硬化患者中极度降低，可以作为一项监测肝炎患者病情轻重的指标。

    关键词 乙型肝炎 AgNORs NK细胞

    Study on the quantity of AgNORs in T lymphocyte cell

    and NK activity in the peripheral blood of hepatits

    B Shi Ming，Zhang Jing，Han Bo，et al.

    Dalian NO.6Hospital，Liaoning116001.

    【Abstract】 Objective To study the change between the quantity of AgNORs in T Lymphocyte cell and NK activity in the peripheral blood of hepatits B.Methods We selected198patients of hepatitis B and30normal peoˉple，whomwere examined the quantity of AgNORs in TLymphocyte cell and NK activity.Results The quantity of AgˉNORs was reduced with the damage of the liver tissue.Among the patients ......