【摘要】 目的 研究血液透析患者IL-6与营养状况的关系。方法 选择61例维持血液透析且无临床感染症状患者，根据超敏C反应蛋白(high sensitive C-reactive protein，hs-CRP)水平分为两组，hs-CRP≥10mg/L组和hs-CRP<10mg/L组，比较两组血清白细胞介素6(interleukin6，IL-6)、转铁蛋白(transferrin，TF)、前白蛋白(pre-albumin，PA)、白蛋白(albuˉmin)、胆固醇(cholesterol)和血红蛋白(Hb)水平，并进行相关性分析。结果 hs-CRP≥10mg/L组血清白细胞介素6、白蛋白、转铁蛋白、前白蛋白水平较hs-CRP<10mg/L组明显降低，差异具有显著性(P<0.01)。且白细胞介素6与血清白蛋白的相关系数r=0.67，P<0.01。结论 血液透析患者IL-6与营养状况密切相关，提示血液透析患者营养不良(特别是低蛋白血症)的发生与透析有关的急性时相反应相关。

    关键词 白细胞介素6 超敏C反应蛋白 血清白蛋白 血液透析

    Ralationship between serum IL-6and malnutrition in hemodialysis patients

    Li Xin，Peng Liren

    Department of Nephrology，Chaoyang Hospital，Beijing100020.

    【Abstract】 Objective To evalute the relationship between serum IL-6levels and malnutrition in hemodialyˉsis patients.Methods High sensitive C-reactive protein(hs-CRP)and IL-6concentration were measured in63hemodialysis patiens who had no obvious inflammation.At the same time，Serum transferring(TF)、pre-albumin(PA)、albumin(Alb)、cholesterol and Hb were measured served as malnutrition indexes.Results IL-6、Alb、TF and PA concertration were significant higher in patients with hs-CRP increased over10mg/L(P<0.01)in a line reˉgression analysis ......