【摘要】 目的 探讨颈动脉灌注红花注射液治疗急性脑梗死的临床疗效。 方法 将100例脑梗死患者随机分为红花注射液颈动脉灌注组(治疗组)50例和红花注射液静脉滴注组(对照组)50例，治疗组:于0.9%氯化钠注射液60ml中加入红花注射液20ml，以4ml/min的滴速经颈动脉灌注;对照组:以红花注射液20ml加入0.9%氯化钠注射液500ml中静滴，20天后对两组疗效进行分析并观察治疗前后肢体肌力及血液流变学变化。 结果 治疗组总有效率为94.0%，优于对照组62.0%(P<0.01)。治疗后治疗组肌力及血液流变学改善明显优于对照组(P<0.05，P<0.01)。 结论 中药红花注射液经颈动脉灌注治疗急性脑梗死的疗效优于静脉全身给药。

    【关键词】 急性脑梗死 颈动脉灌注 红花注射液 中医药疗法

    Curative effect observation of treatment in acute cerebral infartion by safflower injection via carotid artery infusion

    Xu Kailei，Fan Huachang，Shen Wenying，et al.

    Department of TCM，Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine.Shanghai200062.

    【Abstract】 Objective To observe the clinical efficacy of treatment in acute cerebral infarction by Safflower injection via carotid artery infusion.Methods 100cases were randomized into treatment group in which50cases were treated with Safflower injection via carotid artery infusion ......