【摘要】 目的 探讨慢性乙型肝炎血清肝纤维化标志物与中医证型间的关系。 方法 146例经肝活检病理确诊的慢性乙肝患者进行中医辨证分型诊断及血清肝纤维化标志物检测。 结果 (1)病理诊断属轻度慢性乙肝者74例、中度48例、重度24例。(2)中医辨证分型:属肝郁脾虚型58例(39.73%)、肝胆湿热型5例(3.42%)、肝肾阴虚型17例(11.64%)、脾肾阳虚型6例(4.11%)及瘀血阻络型60例(41.10%)。(3)轻度肝损害组，中医辨证以肝郁脾虚型为主，占71.62%(53/74);中度组则以瘀血阻络型为主，占68.75%(33/48);重度组24例，均属瘀血阻络型范畴，只是少数患者伴有其它兼证。血清肝纤维化标志物检测值与中医证型间有显著相关性，瘀血阻络型与其它各型间比较差异均有非常显著性(P<0.01)。 结论 慢性乙型肝炎血清肝纤维化标志物检测与中医证型间有显著相关性，对指导临床慢性肝炎肝纤维化的诊断与治疗具有重要意义。

    关键词 慢性乙型肝炎 肝活检 中医辨证分型 肝纤维化

    Study on relationship among hepatic fibrosis labelling in serum and TCM type of syndrome in patients with chronic hepatitis B.

    Xiao Hejie，Li Congrong，Ren Jianxia，et al.

    Centre of The Liver Disease Prevention and Treatment in the China Electro-Power System，Centre Hospital in Gezhouba，Yichang443002.

    【Abstract】 Objective To study on relationship among hepatic fibrosis labelling in serum and traditional chi-nese medicine(TCM)type of syndrome in patients with chronic hepatitis B.Methods There were146patients with chronic hepatitis B by liver biopsy pathologic diagnosis and TCM differentiation of syndrome.Results There were the low-grade74 ......