【摘要】 目的 探讨肝硬化患者的血清一氧化氮(NO)与低氧血症的关系。 方法 60例肝硬化患者(HC)，30例健康人(HS)，用血气分析测定动脉血氧分压，硝酸还原酶法测定血清NO含量。 结果 肝硬化患者组血清NO含量显著高于健康对照组。肝硬化患者血清NO含量正常组血氧分压显著高于肝硬化患者NO含量异常升高组，且与健康对照组无显著差异。 结论 肝硬化患者血清NO含量升高可能是引起低氧血症的原因之一。

    【关键词】 肝硬化 低氧血症 血清一氧化氮

    A study on the relationship between serum nitric oxide and hypoxemia with cirrhosis

    Jiang Lin，Chen Niwei，Sun Qun，et al.

    Department of Gastroenterology，Shanghai JiaoTong University Attached Shanghai Sixth People's Hospital，Shanghai200233.

    【Abstract】 Objective To explore the relationship between serum nitric oxide(NO)and hypoxemia in pa-tients with cirrhosis.Methods The serum nitric oxide concentration with colorimetrie assay were detected，and the arterial oxygen pressure were determined by arterial blood gas measurements in60patients with cirrhosis(HC)and30healthy subjectives(HS).Results Serum NO were significantly different between patients with cirrhosis and HS group.The arterial oxygen pressure of HC group with normal serum NO were markedly higher than that with abnormal serum NO group.However ......