【摘要】 目的 探讨大肠癌患者免疫功能与分期的关系。方法 采用免疫荧光法和透射比浊法测定60例大肠癌患者和20例正常人的细胞免疫及体液免疫功能。结果 大肠癌患者CD3 + 、CD4 + 、NK、C3、C4、IgG、IgA、IgM、CD4 + /CD8 + 比值降低，CD8 + 高于正常对照组，这种变化随临床分期的增高更加显著(P<0.05)。结论 大肠癌患者存在免疫功能抑制，随临床分期的增高而加重。测定大肠癌患者的免疫功能可以判断肿瘤发展情况与预后。根治性切除肿瘤，行免疫化疗是必要的。

    关键词 大肠癌 免疫功能 T淋巴细胞亚群

    Clinical value of detecting immunologic function

    in patients with colorectal cancer

    Qiang Yaosheng

    Department of General Surgery，Trainway Center Hospital of Lanzhou730000.

    【Abstract】 Objective To study the realationship between the immunologic function and clas sification in paˉtients with colorectal cancer.Methods 60cancer patients and20healthy controls were enrolled in the study.Celluar immunity wasmeasured by immunofluorescence and humoral immunofuction was measured by transmission turbidˉmetey.Results The percen tages of CD3 + 、CD4 + 、NK、C3、C4、IgG、IgA、IgM and the ratio of CD4 + /CD8 + of colˉorectal cancer patients decreased compared with controls ......