【摘要】 目的 探讨早期经颅穿刺引流术对晚发性维生素K缺乏症致颅内出血的疗效。 方法 对36例晚发性维生素K缺乏引致重症颅内出血的患儿随机分成两组，内科治疗组单纯予内科综合治疗，手术治疗组在内科综合治疗基础上，予经颅穿刺引流术，并随访至1～2岁。 结果 手术治疗组治愈率明显高于内科治疗组，手术治疗组死亡率明显降低，手术治疗组后遗症也明显低于内科治疗组，均有统计学意义。 结论 早期经颅穿刺引流可提高晚发性维生素K缺乏致颅内出血的治愈率，有效地降低其死亡率，并提高患儿的生存质量。

    关键词 晚发性维生素K缺乏症 颅内出血 穿刺引流术 疗效 随访

    Early transcranial puncture and drainage on the intracranial hemorrhage caused by delayed vitamin K deficiency

    Pan Yonghuang，Xiao Pei，Wu Liping，et al.

    Department of Pediatrics，Shilong People's Hospital of Dongguan City，Guangdong523321.

    【Abstract】 Objective To discuss the effect of early trans frontal fontanels and labroid suture puncture and drainage on the intracranial hemorrhage caused by delayed vitamin K 1 deficiency.Methods 36children with intracranial hemorrhage caused by delayed vitamin K 1 deficiency were randomly divided into internal treatment group and surgical treatment group.All of patients were followed up to1to2years old.The surgical group were treated with early trans frontal fontanels and labroid suture puncture and drainage based on the internal treatment.Results The healing rate of surgical group was more higher than the internal group.Mortality of the surgical group was greatly decreased.Incidence of the sequelae was also significantly lower than that in the internal group.There were significant differences about heal-ing rate ......