关键词：老年病；胃大部切除术；围手术期；微循环
【摘要 】 目的 从微循环角度探讨老龄心脏疾患大鼠对中大型手术的耐受性。方法 老龄大鼠注射垂体后叶素复制心肌缺血模型，观察胃大部切除术对老龄心肌缺血大鼠围手术期脊斜肌微循环的变化。结果 有心脏疾患的大鼠手术后1h血压明显不降，微循环中第三级动、静脉的血流速度、血液流量和毛细血管开放数明显减少，动、静脉血管口径无明显变化。无心肌缺血的对照老年大鼠手术后，其血压和上述微循环参数无明显改变。结论 根据本实验推测老年患者只要器官功能尚正常，可耐受中、大型腹部手术，但有心肌缺血表现时手术会带来机体微循环的严重紊乱，需要加强围手术期的监护和处理。
The Microcirculation Changes AfterAbdominal Operation in Elderly Rats with Myocardial Ischemia
Huang Xuliang，Shi Hanping，Jin Chunhua，etal.
Department of Pathophysiology，The First Military Medical University.Guangzhou 510515
【Abstract 】 Objective To investigate the influence of medium or major operations on the microcircluation ofelderly rats with myocardial ischemia.Methods The model of myocardialischemia was reproduced by vasopressin administration at a dose of 1 U/1 kg/d bodyweight for 4 days.25-months elderly rats were used to investigate the microcirculationchanges after subtotal gastrectomy.Results It was found that the meanblood pressure ......
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