陈琳洁 唐福林 汪国生 陈琳洁 233004 蚌埠医学院附属医院风湿病科；唐福林 北京协和医院免疫科；汪国生 安徽省立医院风湿科 蚌埠医学院学报 1999 0 24 5


    关键词：Sjogern综合征；发热 期刊 bbyxyxb 0 临床医学 fur -->


    

摘要 目的 ：探讨以发热为首发症状的原发性干燥综合征(PSS)的临床特征，以减少误诊。方法 ：将发热为首发症状的PSS 20例，与同期随机选择无发热的PSS 20例进行对比分析。结果 ：发热组皮疹、浅表淋巴结和腮腺肿大、抗核抗体高滴度阳性、血沉极度增快发生率高于非发热组(P<0.05～P<0.01)；而非发热组口眼干燥和龋齿发生率则高于发热组(P<0.01)。发热组误诊率高达35%；单用激素治疗复发率高，加用免疫抑制剂可降低复发率。结论 ：以发热为首发症状的PSS并非少见，治疗宜联合应用激素和免疫抑制剂。

    中国图书资料分类法分类号 R 781.71

Primary Sjogren's syndrome with fever as the first symptom

Chen Linjie,Tang Fulin,Wang Guosheng

    (Department of Rheumatology,Affiliated Hospital of Bengbu Medical College,Anhui 233004)

Abstract Objective :To study the clinical features of primary Sjogren's syndrome(PSS) with fever as the first symptom for avoiding misdiagnosis.Methods :Compare the clinical features of 20 PSS patients with and without fever.Results :The incidence of skin rash,enlargement of superfical lymph nodes,bilateral swelling of salivary glands,high titre of ANA,and increase in ESR were higher in fever group(P< 0.05～ P< 0.01),whereas the frequency of sicca complex and dental caries were higher in nonfever group(P< 0.01).The rate of misdiagnosis was high(35%) in fever group.The recurrence was high in patients treated with glucocorticoid only,and immunosuppressive agents should be given to reduce the recurrence.Conclusions :Primary Sjogren's syndrome with fever as its first symptom is not rare.Glucocorticoid and immunosuppressive agents should be used in combination for treatment.

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