【摘要】 目的 为了加速控制麻疹。方法 安徽省1997年度对三个地市1～6岁儿童进麻疹疫苗(MV)强化免疫，并随后开展了全省麻疹监测。应用酶联免疫吸附法(ELISA)检测麻疹、风疹IgM抗体，微量血凝抑制试验检测麻疹IgG抗体。结果 强化免疫后麻疹抗体阳性率上升到100%，GMT从1∶18.97增长到1∶43.45；1998年上半年麻疹发病数比1997年同期下降了87.71%，并控制了爆发，检测181例发热出疹性病例的血清，其中麻疹IgM阳性105例，占58.01%，风疹IgM阳性32例，占17.68%。结论 在保持高水平的MV常规免疫时，开展麻疹疫苗强化免疫，建立并逐步完善麻疹监测系统，加强风疹预防工作，是加速控制麻疹的重要策略。

    

【Abstract】 Objective To speed up measlescontrol progr am. Methods Catching-up immunization campaigns onmeasles have been conducted among the children aged 1-6 years in three prefectures of Anhui by the end of 1997 and the measles surveillance system was established at th ebeginning of 1998. IgM antibody of measles and rubella was tested with ELISA a nd IgGantibody was examined with HI test. Results The po sitive rate ofmeasles antibody among children was 100%, GMT increased from 1∶18.97 to 1∶43.45 afterthe campaigns. Measles cases in the three districts f rom January to June 1998 had a87.71% decrease, comparing with the same period o f 1997 with measles outbreak avoided.There were 105(58.01%) cases of measles with positive IgM and 32(17.68%) cases of rubellawith positive IgM out of 1 81 testees having fever and rash illnesses.Conclusion Results indicated that programs as catching-up immunization campaigns on measles an d keepinghigh level of MV immunization, establishing measles surveillance syste m with improvementof its sensibility together with rubella control program all seemed to be importantstrategies in speeding up the positive outcome of mea sles control.

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