【摘要】 目的 探讨生物胶粘贴缝合双层羊膜遮盖防治外伤性角膜穿孔的可行性。方法 15例(18眼)角膜损伤患者实施双层羊膜移植，其中角膜穿孔者14眼，深层溃疡达角膜1/3基质以上者4眼。小片羊膜覆盖在溃疡或穿孔处，将生物胶滴于羊膜、角膜表面，并将大片羊膜迅速贴于角膜表面。10/0尼龙线间断缝合大片羊膜于结膜创缘及浅层巩膜上。结果 所有患者视力均优于术前。术中及术后未见特殊并发症。结论 双层羊膜粘贴缝合治疗和预防外伤性角膜穿孔，操作简单，效果显著。

    【关键词】 羊膜；移植；角膜穿孔

    Modified amniotic membrane overlay transplantation for preventing and treating traumatic cornea perforation

    WANG Jia-yu,YANG Jian-dong,CAO Li，et al.

    Department of Ophthalmology, The 81th Hospital of PLA, Nanjing 210002, China

    【Abstract】 Objective To study the feasibility of biological adhesive in fixation of two-layer amniotic membrane transplantation(AMT) for preventing and treating traumatic cornea perforation.Methods Two-layer AMT was performed in 15 patients(18 eyes)with corneal injury, 14 eyes with traumatic cornea perforation, and 4 eyes with severe corneal ulcer upward of 1/3 corneal matrix. A small piece of amniotic membrane was covered on the focus, and a large one on the whole cornea by biological adhesive. The large amniotic membrane was sutured interruputedly to the traumatic edge of conjunctiva and superficial sclera by 10/0 nylon suture line.Results Vision of all patients was improved. No specific complications were found in the operation and after operation.Conclusion Two-layer AMT by biological adhesive is a very effective method to treat and prevent traumatic cornea perforation and operation is simple. ......