当前位置: 首页 > 期刊 > 《世界华人消化杂志》 > 2005年第19期 > 正文
编号:10924702
内镜下双重色素法联合超声内镜对食管早期癌及癌前病变的诊断价值
http://www.100md.com 刘一品, 黄留业, 李延青
双重色素法; 超声内镜; 早期食管癌; 癌前病变刘一品,黄留业,李延青.内镜下双重色素法联合超声内镜对食管早期癌及癌前病变的诊断价值.世界华人消化杂志2005;13
第1页

    参见附件(761KB,3页)。

     刘一品, 黄留业烟台毓璜顶医院消化内科山东省烟台市 264000

    李延青,山东大学齐鲁医院消化内科山东省济南市 250012

    通讯作者:刘一品, 264000,山东省烟台市芝罘区毓璜顶东路20号,烟台毓璜顶医院消化内科. yipinliu@tom.com

    电话:0535-6691999-82703 传真: 0535-6240341

    收稿日期:2005-07-15 接受日期:2005-08-03

    Evaluation ofdouble staining combined with endosonography in detection of earlyesophageal cancer and precancerous lesions

    Yi-Pin Liu, Liu-Ye Huang, Yan-Qing Li

    Yi-Pin Liu, Liu-Ye Huang, Department of Gastroenterology,Yuhuangding Hospital of Yantai, Yantai 264000, Shandong Province, China

    Yan-Qing Li, Department of Gastroenterology, Qilu Hospital ofShandong University, Ji’nan 250012, Shandong Province, China

    Correspondence to: Dr. Yi-Pin Liu, Departmentof Gastroenterology, Yuhuangding Hospital of Yantai, 20 Yuhuangding EastRoad, Zhifu District, Yantai 264000, Shandong Province, China.yipinliu@tom.com

    Received: 2005-07-15 Accepted: 2005-08-03

    Abstract

    AIM: To investigate the effect of double staining, methylene blueand Lugol’s solution, combined with endosonography in the detection ofearly cancer and precancerous lesions of esophagus.

    METHODS: Ninety-six patients with doubtful esophageal diseaseswere involved in this study. The lesions were firstly treated withmethylene blue (20 g/L) and then Lugol’s solution (30 g/L). Biopsieswere performed in the parts stained by methylene blue but unstained byLugol’s solution. Endosonography was also performed in the patientsdiagnosed with esophageal cancer, severe atypical hyperplasia, andBarrett’s esophagus.

    RESULTS: Seven patients with esophagus cancer (including 2 casesof early cancer), 14 with atypical hyperplasia (7 light, 4 moderate, 3severe), 3 with Barrett’s esophagus, 8 with ulcer and 36 withinflammation. The total positive rate of double staining is 70.8%. Theaccuracy rate of endosonography is 92.3% (12/13) in detecting theinfiltration depth and the mediastinal lymph node metastasis of earlyesophageal cancer and precancerous lesions.

    CONCLUSION: The double staining of methylene blue and Lugol’ssolution combined with endosonography is helpful in the diagnosis ofesophageal diseases, especially the early cancer and precancerous lesions.

    Key Words: Double staining; Endosonography; Early esophagealcancer; Precancerous lesions

    Liu YP, Huang LY, Li YQ. Evaluation of double staining combined withendosonography in detection of early esophageal cancer and precancerouslesions. Shijie Huaren Xiaohua Zazhi 2005;13(19):2386-2388

    摘要


    目的:探讨美蓝和卢戈氏碘液双重染色法联合超声内镜对食管早期癌及癌前病变的诊断价值.

    方法:对96例可疑食管病变患者行食管黏膜染色, 先用20 g/L美蓝喷洒, 再用30 g/L卢戈氏碘溶液喷洒于病变区观察; 对美蓝染色区和卢戈氏碘不染色区进行活组织病理检查.食管癌及重度不典型增生、Barrett食管等癌前病变者再次行超声内镜检查 .

    结果:
确诊为食管癌7例, 其中早期癌2例; 不典型增生14例(轻度7例, 中度4例, 重度3例); Barrett食管3例; 溃疡8例;炎症36例.双重染色法总阳性率达70.8%.超声内镜对判断食管癌及癌前病变的浸润深度及纵隔淋巴结转移准确率达92 ......

您现在查看是摘要介绍页,详见PDF附件(761KB,3页)