【摘要】 目的 探讨冠心病合并2型糖尿病患者冠脉病变程度与C-反应蛋白(CRP)的关系及经皮冠状动脉介入治 疗(PCI)后的变化。 方法 采用酶联免疫吸附试验(ELISA)测定经皮冠状动脉造影(CAG)确诊并行PCI术的患者及32例 CAG正常者的血清hsCRP水平，并比较不同冠脉病变程度者其血清值及PCI术后的变化。 结果 研究组中的双支及多支 病变组明显高于正常对照组，PCI术后显著高于术前。 结论 血清hsCRP水平与冠心病合并2型糖尿病冠脉病变程度密 切相关。在冠脉粥样硬化的过程中有炎症反应参与，在PCI术后应加强干预。

    【关键词】 冠心病;糖尿病;C-反应蛋白;经皮冠状动脉介入治疗

    Contrasted study of serum levels of hsCRP in patients with coronary heart dis- ease and type 2 diabetes before and after PCI

    ZHAI Ji-min，LIU Chuan-mu，ZHANG Ming-zhe.

    Department of Cardiology，Shandong Provincial Shengli Oil Field Central Hospital，Dongying 257000，China

    【Abstract】 Objective To observe the change of C-reactive protein(hsCRP) plasma level before and after percutanous coronary intervention(PCI) in patient with coronary heart disease with type 2 diabetes， to evaluate the relationships between the severity of coronary lesions. Methods 50 patients diagnosed as angina pectoris by coronary angiography received PCI and 32 healthy subjects served as the control.Peripheral blood samples were taken before and after PCI ......