【摘要】 目的 探讨胸水C反应蛋白(CRP)、乳酸脱氢酶(LDH)、胆固醇(TCH)在胸水性质鉴别中的应用。方法 检测70例胸腔积液患者胸水CRP、LDH、TCH三项生化指标。结果 恶性组C反应蛋白(CRP)、乳酸脱氢酶(LDH)、胆固醇(TCH)测定结果分别是11.0±18.2mg/L、501.0±304.1u/L、2.15±0.81mmol/L；良性组测定结果分别是26.1±21.0mg/L、310.2±185.4u/L、1.63±0.49mmol/L,CRP在良性胸水中明显升高与恶性胸水检测结果相比P<0.01；LDH、TCH在恶性胸水中显著升高与良性胸水相比P<0.01。结论 CRP、TCH、LDH联合检测在胸水性质鉴别中有一定的临床价值。

    【关键词】 胸水；C反应蛋白；乳酸脱氢酶；胆固醇

    【Abstract】 Objective To investigate the function of CRP、LDH and TCH in pleural fluid on differentiating the character pleural fluid.Methods The levels of pleural fluid CRP、 LDH and TCH were detected in 70 pleural effusion patients.Results In malignant group,the levels of CRP、LDH and TCH were 11.0±18.2mg/L、501.0±304.1u/L、2.15±0.81mmol/L respectively; In benign group the levels of CRP、LDH and TCH were 26.1±21.0mg/L、310.2±185.4u/L、1.63±0.49mmol/L respectively, CRP was increased significently of benign pleural fluid compared with that of malignant group (P<0.01); LDH and TCH were increased highly compared with that of benign pleural fluid (P<0.01).Conclusion Combination of detecting CRP、 LDH and TCH of pleural fluid may be valuable to distinguish the charactor of pleural fluid. ......