降纤酶治疗急性脑梗死临床观察
降纤酶,,降纤酶；急性脑梗死；血液流变学,1资料与方法,2结果,3讨论,【参考文献】
【摘要】 目的 比较降纤酶与丹参治疗急性脑梗死的疗效。方法 随机选择92例急性脑梗死患者分成两组，治疗组48例静滴降纤酶5U加入生理盐水250ml静滴，连用7天，首次剂量加倍；对照组44例静滴丹参注射液20ml加入生理盐水250ml静滴，连用10天；治疗组用药前后测定血液流变学。结果 降纤酶组治疗总有效率明显优于对照组(P<0.05)；降纤酶组治疗后血液流变学结果下降差异均有显著性(P<0.05)或非常显著性(P<0.01)。结论 降纤酶是治疗急性脑梗死的一种安全有效药物。【关键词】 降纤酶；急性脑梗死；血液流变学
Clinical observation of defibrase on treating acute cerebral infarction
MIAO Sheng-ju，XU Ling，QU Yinzong.
Xinhua Hospital Of Hubei,Wuhan 430015,China
【Abstract】 Objective To compare the effect of defibrase on treating acute cerebral infarction with Danshen. Methods 92 patients with acute cerebral infarction were divided randomly into 2 groups, 48 patients were injected with defibrase 5u in 0.9% sodium chloride 250ml,iv drip qd×7d as a course, with double first dose; 44 patients were injected with Danshen 20ml in 0.9% sodium chloride 250ml, iv drip qd×10d as a course in control group. Before or after treatment, hemorheology was checked in defibrase group. Results The effective rate of defibrase group is far higher than control group (P<0.05). The hemorheology is improved apparently (P<0.05) or markly (P<0.01) after adiministration in the defibrase group.Conclusion Defibrase is safe and efficient medicine on the treatment of acute cerebral infarction. ......
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