【摘要】 目的 评价胼胝体面积测量对判断2型糖尿病老年患者早期认知功能损害的价值。方法 14例2型糖尿病老年患者和9例正常老年人对照，进行MRI扫描并全部行简易认知状态检查表(MMSE)、数字广度测验(DS)检查。结果 2型糖尿病老年患者组胼胝体面积区域性减少，胼胝体萎缩与2型糖尿病老年患者的认知功能损害显著相关。结论 磁共振成像胼胝体面积的测量有助于临床正确评价2型糖尿病老年患者早期认知功能的损害。

    【关键词】 磁共振成像；胼胝体；测量；糖尿病

    MRI study on corpus callosum size in elderly type Ⅱ diabetic patients with cognitive impairment

    LIU Han-qiu，SUN Hua-ping，FENG Xiao-yuan，et al.

    Department of Radiology，the Affiliated Huashang Hospital of Fudan University，Shanghai 200040，China

    【Abstract】 Objective To detect the value of the area-measurement of corpus callosum by MR imaging for early discovery of the cognitive functional impairment.Methods Fourteen old patients with type Ⅱ diabetes and 9 matched normal control were studied with MRI and mini-mental state examination(MMSE) and Digit Span(DS) test.Results The corpus callosum size were significantly reduced in old patients with type Ⅱ diabetes.Significant correlates were observed among the size of corpus callosum and MMSE and DS.Conclusion The measurements of corpus callosum size by MRI can help to evaluate the degree of cognitive dysfunction in old diabetic patients. ......