【摘要】 目的 采用表面修饰技术对硅凝胶人工晶体进行钛及钛基复合材料表面修饰，以开拓新型人工晶体。方法 选择血小板黏附实验、巨噬细胞黏附实验以及硅油表面黏附实验，进行体外细胞毒性实验。结果 修饰的人工晶体表面血小板、巨噬细胞以及硅油黏附少于未修饰的硅凝胶人工晶体。结论 表面修饰提高了硅凝胶人工晶体的生物相容性。

    【关键词】 表面改性；人工晶体；生物相容性

    The evaluation of the biocompatibility on the surface modified intraocular lenses

    WANG Gui-qin，GU Han-qing，PENG Xiu-jun.

    Department of Ophthalmology, The Naval General Hospital, Beijing 100037, China

    【Abstract】 Objective To develop a newly intraocular lenses (IOLs) silicone IOLs were modified with titanium and titanium nitride by the technique of surface modification.Methods In vitro cellular toxic experiment was performed with platelets, macrophages and silicone oil adherence to IOLs.Results The modified IOLs had less adherence to platelets, macrophages and silicone oil than the unmodified IOLs.Conclusion The biocompatibility of the silicone IOLs was improved by surface modification.

    【Key words】 surface modification；intraocular lenses; biocompatibility

    随着生物医学工程的发展 ......