骨折愈合_____骨折愈合；_骨折固定术；

持续动态压应力对实验性骨折愈合的影响

http://www.100md.com 《第四军医大学学报》 2004年第1期

骨折愈合,,骨折愈合；,骨折固定术；,生物力学；,分子生物学；,形状记忆合金,0引言,1材料和方法,2结果,3讨论,【参考文献】

     ·研究原著·

    Effect of continuous dynamic compressive stress on femoral fractures healing in dogs

    REN Ke, ZHANG ChunCai, XU ShuoGui, TANG Hao, KANG QingLin, GAO TangCheng, ZHANG XueSong

    Department of Orthopaedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China

    【Abstract】 AIM: To explore the effect and mechanism of continuous dynamic pressure stress on femoral fractures healing in dogs. METHODS: Bilateral femoral of 15 adult dogs were osteotomized in the middle and then 1 femur was randomly internal fixed with swanlike memory connector (SMC) while the contralateral side fixed with Kuntscher intramedullary nails. Five animals in each group were sacrificed at 7, 14, 21, 28, 49 d after operation. Samples from the fracture gaps were obtained and histological and molecular biological techniques (expression of the mRNA of the cartilagespecific collagen IX and osteocalcina marker for mature osteoblasts) were employed. RESULTS: In terms of histology and molecular biology, the chondrogenesis in the fracture gap continued for shorter period and the enchondral ossificassion were strengthened in fractures fixed with SMC. CONCLUSION: The persistent dynamic longitudinal pressure stress produced by SMC may contribute to the process of healing of long bone. ......

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