Epidemiological study on pathogenic bacteria in the nosocomial infection from 1999 to 2002

    WAN Jianª²Hua, ZHANG Jingª²Ping, CHEN Baiª²Yi

    Department of Infectious Diseases, First Affiliated Hospital, China Medical University, Shenyang 110001, China

    ¡¾Abstract¡¿ AIM: To investigate the dynamic changes in the distribution and resistance of bacilli responsible for the nosocomial infection and to offer a basis for the empirical treatment of bacterial infection. METHODS: Kª²B test was used for the antibiotics susceptivity test and the results were recorded based on National Committee for Clinical Laboratory Standards (NCCLS) and analyzed with WHONETª²5 software. RESULTS: The pathogens responsible for the nosocomial infection were mainly Gramª²negative bacteria during the 4 years from 1999 to 2002. They were resistant to 16 kinds of studied antibiotics. The resistant rate of methicillinª²resistant Staphylococcus aureus (MRSA), methicillinª²resistant Staphylococcus epidermidis (MRSE) and extendedª²spectrum betaª²lactamases (ESBLs)ª²producing strains markedly increased, but there were no obvious changes in the distribution and resistance of those pathogens mentioned above. CONCLUSION: The resistant rate of MSRA,MSRE and ESBLsª²producing bacilli has increased markedly. ......