MnDPDP enhanced magnetic resonance imaging of focal liver lesion

    LIU Yanª²Li, HUAN Yi, GE Yaª²Li, WEI Guangª²Quan, CHANG Yingª²Juan, ZHANG Jingª²Song, ZHAOª²Haiª²Tao

    Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi¬ðan 710033, China

    ¡¾Abstract¡¿ AIM: To study the MnDPDP enhanced magnetic resonance imagings and to assess their diagnostic value in MR examination. METHODS: Thirteen patients with hepatic lesions were included in this study, 11 cases of which had been confirmed by either operation or biopsy. T1WI (T1ª²FFE, T1ª²TFE ) and T2WI (T2ª²TSE) were performed prior to the administration of contrast agent. T1ª²weighted images were then obtained at 20 min and 24 h following intravenous infusion of 0.5 mL/kg MnDPDP. RESULTS: Six cases of hepetocellular carcinoma showed detectable enhancement with MnDPDP, varying patterns of enhancement were obtained. In 1 case of focal nodular hyperplasia (FNH) and 1 case of hepatocellular adenoma, lesions appeared isoª²intense or hyperª²intense compared with normal liver in earlyª²phase imaging. In 2 cases of liver haemangioma and 3 cases of liver metastases, lesions did not enhance with MnDPDP. CONCLUSION: As a new contrast agent used in magnetic resonance imaging of the liver, MnDPDP is of some value in detecting hepatic lesions and in differential diagnosis. ......