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围手术期输血对非小细胞肺癌患者术后无病生存的影响
http://www.100md.com 《第四军医大学学报》 2004年第11期
非小细胞肺癌,,输血;无病生存期;非小细胞肺癌,0引言,1对象和方法,2结果,3讨论
     Influence of perioperative blood transfusion on diseasefree survival in nonsmall cell lung cancer patients

    JIAO ShunChang, ZHANG WenQin, YANG JunLan, ZHAO Hong, LI Fang, DAI GuangHai, LI Ying, WEI XiuFang

    1Department of Oncology, PLA General Hospital, Beijing 100853, China, 2Department of Internal Medicine, Fourth Hospital, Handan City, Handan 056200, China

    【Abstract】 AIM: To study the influence of perioperative allogeneic blood transfusions on diseasefree survival in nonsmall cell lung cancer patients treated with curative pulmonary resection. METHODS: Among the 70 patients with primary nonsmall cell lung cancer, 53 (75.7%) received allogeneic blood products. Multivariate Cox regression model was used to analyze the diseasefree survival and to draw survival curves. RESULTS: In the multivariate analysis, differentiation, stage and postoperation adjuvant treatment were found to be the significant factors affecting the prognosis (P<0.05), whereas the blood transfusion and other factors were not significant (P>0.05). The survival curves showed that perioperative allogeneic blood transfusions decreased the diseasefree survival in nonsmall lung cancer patients (P>0.05). CONCLUSION: Perioperative allogeneic blood transfusions may decrease the diseasefree survival in nonsmall lung cancer patients. If possible, surgeons should avoid using perioperative allogeneic blood transfusion. ......

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