围手术期输血对非小细胞肺癌患者术后无病生存的影响
非小细胞肺癌,,输血;无病生存期;非小细胞肺癌,0引言,1对象和方法,2结果,3讨论
Influence of perioperative blood transfusion on diseasefree survival in nonsmall cell lung cancer patientsJIAO ShunChang, ZHANG WenQin, YANG JunLan, ZHAO Hong, LI Fang, DAI GuangHai, LI Ying, WEI XiuFang
1Department of Oncology, PLA General Hospital, Beijing 100853, China, 2Department of Internal Medicine, Fourth Hospital, Handan City, Handan 056200, China
【Abstract】 AIM: To study the influence of perioperative allogeneic blood transfusions on diseasefree survival in nonsmall cell lung cancer patients treated with curative pulmonary resection. METHODS: Among the 70 patients with primary nonsmall cell lung cancer, 53 (75.7%) received allogeneic blood products. Multivariate Cox regression model was used to analyze the diseasefree survival and to draw survival curves. RESULTS: In the multivariate analysis, differentiation, stage and postoperation adjuvant treatment were found to be the significant factors affecting the prognosis (P<0.05), whereas the blood transfusion and other factors were not significant (P>0.05). The survival curves showed that perioperative allogeneic blood transfusions decreased the diseasefree survival in nonsmall lung cancer patients (P>0.05). CONCLUSION: Perioperative allogeneic blood transfusions may decrease the diseasefree survival in nonsmall lung cancer patients. If possible, surgeons should avoid using perioperative allogeneic blood transfusion. ......
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