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免疫印迹法检测IKK, IκB和NFκB在喉癌中的表达
http://www.100md.com 《第四军医大学学报》 2004年第23期
喉肿瘤,,喉肿瘤;免疫印迹法;IKB激酶;IκB;核因子κB,免疫印迹法检测IKK,IκB和NFκB在喉癌中的表达,0引言,1材料和方法,2结果,3讨论,【参考文献】
     Expression of IKK, IκB and NFκB in laryngeal carcinomas: A Western blot study

    ZHU Jiang, HU GuoHua, SUN YuCai

    1Department of Otolaryngology, First Hospital, Chongqing University of Medical Sciences, Chongqing 400016, China, 2Department of Otolaryngology, Affiliated Hospital, Jinin Medical College, Jinin 272129, China

    【Abstract】 AIM: To detect the expression of IKK, IκB and NFκB in laryngeal carcinomas and to explore its significance for the genesis and development of carcinomas. METHODS: The expression of IKKα, IκBα and NFκB p65 in 20 cases of laryngeal carcinomas and 10 cases of normal laryngeal tissues was detected by Western blot technique. RESULTS: The expression of IKKα and NFκB p65 in laryngeal carcinoma tissues was higher compared with that in normal laryngeal tissues and the expression of IκBα was lower (P<0.05). CONCLUSION: The expression imbalance of IKK, IκB and NFκB is closely associated with the genesis and development of laryngeal carcinomas. ......

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