Changes of transcranial doppler sonography and brainª²stem auditory evoked potential in patients with migraine attack

    YANG Qian

    Department of Neurology, Shaanxi People¬ðs Hospital, Xi¬ðan 710068, China

    ¡¾Abstract¡¿ AIM: To study the changes of transcranial doppler sonography (TCD) and brainª²stem auditory evoked potential (BAEP) in patients with migraine attack and their clinical significance. METHODS: Data were analyzed in 350 patients (male 128, female 222, aged from 17 to 49) with migraine attack, of whom 185 cases had classical migraine (oneª²side 105, twoª²side 80) and 165 (oneª²side 95, twoª²side 70) cases had common migraine. One hundred and thirtyª²five (male 55, female 80, aged from 20 to 48) subjects under routine medical checkª²up served as controls. Both the patients and controls had TCD and BAEP functional examinations. RESULTS: In the 350 cases of migraine attack, fast cerebral blood flow was observed in 224 cases (64.0%), slow cerebral blood flow was observed in 110 cases (31.4%) and normal in 16 cases (4.6%), with the total abnormity rate reaching 95.43%. In patients with classical migraine, MCA (cm/s, middle cerebral artery) and PCA (cm/s, posterior cerebral artery) were significantly higher than those in controls [(70¡À7) vs (62¡À8), P<0.05; (48¡À9) vs (37¡À8), P<0.05] and those with common migraine(61¡À6, P<0.05; 40¡À9, P<0.05) respectively. In patients with attack, BAEP abnormity rate was 52.9% (185/350), displaying prolongations of latency phase in ¢ñ, ¢ó and ¢õ waves and in ¢óª²¢õ interspike interval. BAEP was normal during migraine attack. The course of disease in the patients was associated with BAEP changes and auditory nerve lesion. CONCLUSION: In patients with migraine attack, there are changes of part cerebral blood flow and BAEP. The disease course is associated with BAEP changes and auditory nerve lesion, indicating that TCD and BAEP may be important indices for clinical diagnosis of migraine. ......