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编号:10949002
雷帕霉素洗脱支架临床应用1年随访
http://www.100md.com 《第四军医大学学报》 2005年第22期
冠状动脉疾病,,西罗莫司;支架;冠状动脉疾病,0引言,1对象和方法,2结果,3讨论,【参考文献】
     One year followup on the efficacy and safety of CypherTM stent applied to treat coronary heart disease

    ZHAO HuiQiang, JIA GuoLiang, GUO WenYi, WANG HaiChang, LI WeiJie, LUAN RongHua, L AnLin, LI ChengXiang, LI Hu, WANG XiaoYan

    Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xian 710033, China

    【Abstract】 AIM: To investigate the efficacy and safety of rapamycin eluting stents (CypherTM) during 1year followup. METHODS: The immediate angiographic and clinical followup outcomes were analyzed retrospectively in 112 patients who had received CypherTM. RESULTS: One hundred and seventythree lesions were treated and 227 stents were implanted in the 112 patients. One hundred and fiftynine slow release rapamycin eluting stents were implanted in 132 lesions. The CypherTM stents were successfully implanted in 156/159 lesions (98.1%). High pressure balloon was used for stent deployment in 2 lesions with severe calcification. Dissection occurred at the distal side of stent in 1 lesion. No serious complications were found during operation and hospitalization. Clinical followup of 102 patients was conducted for 12 months and 1 patient died of cardiac death and angina pectoris occurred in 10 patients. Angiography was conducted again in the all 10 patients, and 6 restenosis in bare stents and 4 new lesions in other coronary arteries were found. Angiography was performed for a second time in 30 of 112 followedup patients, showing only 1 restenosis in CypherTM stent. CONCLUSION: CypherTM is safe and effective in the treatment of coronary lesions. ......

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