关键词: 冠状动脉疾病;血管成形术，经腔，经皮冠状动脉;磁化支架;冠状血管/损伤

    摘 要:目的 探讨磁化支架对(PTCA，Percutaneous trans-luminal coronary angioplasty)术后冠状动脉再狭窄的防治作用. 方法 20只健康杂种犬，超大球囊反复扩张损伤靶血管(前降支或旋支中段)制备PTCA术后冠状动脉狭窄模型(大于50%)后随机分成对照组和实验组各10只，对照组靶血管置入普通Palmaz支架，实验组靶血管置入磁化Palmaz支架.手术前、后不用抗血小板药和抗凝药，术后6mo冠状动脉造影并处死犬，切取靶血管3cm进行组织病理学检查. 结果 冠状动脉造影示冠状动脉再狭窄率对照组30%，实验组0;组织病理学检查靶血管平均内膜厚度[对照组(2.98±0.56)mm，实验组(1.13±0.41)mm]有显著差异，P<0.05. 结论 磁化支架对犬PTCA术后冠状动脉再狭窄有显著的防治作用.

    Experimental study of magnetic stent preventing coronary restenosis after PTCA

    LU An-Lin，JIA Guo-Liang，GUO Wen-Yi，YANG Sheng-Li，WANG Xiao-Yan，HU Tao

    Department of Cardiovasology，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:coronary disease;angioplasty，transluminal，per-cutaneous coronary;magnetic stent;coronary vessels/injury

    Abstract:AIM To investigate the preventive effect of mag-netic stent on coronary restenosis after percutaneous translu-minal coronary angioplasty(PTCA).METHODS Twenty dogs were randomly distributed to control and experimental groups ......