移植_____肝移植；腹腔镜；动物，实验；猪

活体肝移植供肝腹腔镜切取术的实验研究

http://www.100md.com 《腹腔镜外科杂志》 2005年第6期

移植,,肝移植；腹腔镜；动物，实验；猪,1资料与方法,2结果,3讨论,参考文献：

     【摘要】目的：探讨腹腔镜活体供肝切取的技术及可行性。方法：运用腹腔镜对猪(n=2)进行左肝切取，操作参照人活体肝移植供体要求进行，观察手术过程中供体生命体征，总腹腔镜操作时间、左肝管道系统分离时间、肝组织分离时间、供肝温缺血时间及术中出血量，并测量供肝质量参数。结果：(1)手术过程中动物血压、呼吸、心率、血气参数稳定，较顺利地取出活体供肝，出血量较少；(2)切取的供肝左肝动脉长约18cm及16cm，左肝门静脉长约10cm及08cm，左肝管约08cm及06cm，左肝静脉约03cm及02cm。经左肝动脉及门静脉灌注良好，温缺血时间为5min及4min。结论：从技术层面而言，腹腔镜下猪活体取肝是可行的。

    【关键词】肝移植；腹腔镜；动物，实验；猪

    Laparoscopic living donor hepatectomy for liver transplantation in porcine

    WANG Chengyou,ZHANG Minjie,LIANG Haohui,et al.

    Department of Hepatobiliary Surgery,Shenzhen Second People's Hospital,Shenzhen 518035, China

    【Abstract】Objective:To study the techniques and feasibility of laparoscopic living donor hepatectomy.Methods:Two pigs were studied and laparoscopic left hepatic lobectomy performed.The procedure was conferred to human.The vital signs were monitered.Time of operation,dissection of left heptic blood vessels and heptic duct,dissection of liver parenchyma,and warm ischemia was recorded,blood loss and the left liver was measured.Results:(1)The vital signs were stable and safe, and the operations were performed successfully with a blood loss of 200ml.(2) The lengths of left hepatic artery were 1.8cm and 1.6cm, left portal vein 1.0cm and 0.8cm,hepatic duct 0.8cm and 0.6cm,hepatic vein 0.3cm and 0.2cm,and the perfusion of left livers was satisfied.The warm ischemia times were smin and 4min.Conclusions:The porcine laparoscopic living donor hepatectomy is feasible from a technical perspective. ......

百拇医药网 http://www.100md.com/html/DirDu/2006/03/23/95/59/51.htm

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