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C反应蛋白与冠心病的关系
http://www.100md.com 《中华实用医药杂志》 2005年第24期
冠心病,,IL-6;冠心病,1研究对象与研究方法,2结果,【参考文献】
     【摘要】 目的 探讨C反应蛋白(CRP)与冠心病的关系。方法 采用微粒增强免疫比浊法测定血浆CRP浓度。检验急性冠脉综合征(ACS)组、稳定型心绞痛(SA)组和对照组中CRP血浆浓度的差异。结果 (1)急性冠脉综合征组和稳定型心绞痛组CRP血浆浓度均高于对照组(P<0.01)。(2)急性冠脉综合征组CRP血浆浓度高于稳定型心绞痛组(P<0.01)。结论 冠心病患者CRP血浆浓度升高,其升高可促进动脉粥样斑块的不稳定,导致急性冠脉综合征的发生,参与冠心病的发生发展过程,并在评估CHD发生的危险性中具有重要地位。

    【关键词】 IL-6;冠心病

    【Abstract】 Objective To study relationships of C-reactive protein(CRP) and coronary heart disease(CHD).Methods The concentrations of plasma CRP were determined by particle-enhanced immunophelometry.Results The concentrations of plasma CRP in the acute coronary syndrome group,the stable angina group were higher than those of the control group. The concentrations of plasma CRP in the acute coronary syndrome group were higher than those of stable angina group.Conclusion The increase of CRP concentration in plasma can promote the attack of CHD and increment of instability of the atherosclerotic plaque which will then cause the attack of ACS.

    【Key words】 C-reactive protein;coronary artery disease

    冠心病是威胁人类健康的重要疾病 ......

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