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编号:11123887
宫内缺氧对子代大鼠脂肪肝发病的影响
http://www.100md.com 苏瑞娟, 吕国荣, 王振华, 李伯义, 刘彦英,
宫内缺氧;脂肪肝;超声直方图苏瑞娟,吕国荣,王振华,李伯义,刘彦英,何韶铮,金鹏.宫内缺氧对子代大鼠脂肪肝发病的影响. 世界华人消化杂志2006;14(11)1048-1051,宫内缺氧对
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     苏瑞娟, 吕国荣, 王振华, 李伯义, 刘彦英, 何韶铮, 金鹏, 福建医科大学附属第二医院超声科 福建省泉州市

    福建省自然科学基金资助课题, No. C0540002

    通讯作者: 吕国荣, 362000, 福建省泉州市, 福建医科大学附属第二医院超声科. sulon1015@yahoo.com.cn

    电话: 0595-22525702

    收稿日期: 2006-02-06 接受日期: 2006-02-13

    Influence of intrauterine hypoxia on pathogenesis of fatty liver in offspring rats

    Rui-Juan Su, Guo-Rong Lv, Zhen-Hua Wang, Bo-Yi Li, Yan-Ying Liu, Shao-Zheng He, Peng Jin

    Rui-Juan Su, Guo-Rong Lv, Zhen-Hua Wang, Bo-Yi Li, Yan-Ying Liu, Shao-Zheng He, Peng Jin, Department of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 36200, Fujian Province, China

    Supported by the Natural Science Foundation of Fujian Province, No. C0540002

    Correspondence to: Guo-Rong Lv, Department of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 36200, Fujian Province, China.sulon1015@yahoo.com.cn

    Received: 2006-02-06 Accepted: 2006-02-13

    AbstractAIM:To study the roles of simple fetal hypoxia, or combined with high-fat diet and the second hypoxia, in adiposis hepatica of offspring rats.

    METHODS: Rat intrauterine hypoxia models were established, and then their offspring were exposed to high-fat diet or/and second hypoxia. The histogram of hepatic ultrasound was measured by B-ultrasound examination. Pathological observation was performed by HE staining for calculating the number of fatty degenerative hepatic cells in the offspring rat with CMIAS system ......

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