非淋菌性尿道炎支原体分离及药敏试验分析
非淋菌性尿道炎,,]非淋菌性尿道炎；解脲支原体；人型支原体；药物敏感性,1对象及方法,2结果,3讨论,[参考文献]
[摘要]目的：探讨非淋菌性尿道炎(NGU)患者支原体的感染率及其对常用药物的敏感性。方法：对326例NGU患者的生殖泌尿标本进行支原体培养及药敏试验。结果：支原体培养阳性142例(43.56%)，解脲支原体(Uu)阳性110例(33.74%)，人型支原体(Mh)阳性14例(4.29%)，Uu+Mh混合感染阳性18例(5.52%)；女性支原体阳性率(52.19%，228例)显著高于男性(23.47%，98例)。药敏结果显示支原体对常用抗菌药物均有不同程度的耐药性。结论：支原体是引起非淋菌性尿道炎的主要病原体，对多种常用抗生素已产生不同程度的耐药性，临床上应根据药敏试验合理、规范用药。[关键词]非淋菌性尿道炎；解脲支原体；人型支原体；药物敏感性
Separation of mycoplasma nongonococcal urethritis and analysis of drug sensitivity test
CHEN Ting, XU Xiaoping
(Neural Internal Medicine, the 2nd People's Hospital, Shenzhen 518035，China)
Abstract: Objective: To investigate infection rate of mycoplasma among patients with nongonococcal urethritis and to analyze sensitivity of common antibiotics. Methods: Urine specimen of 326 cases with NGU were collected and cultured for isolation and identification of germs. Drug sensitivity tests were performed with microdilution plates. Results: For the male patients, positive rates for mycoplasma, ureaplasma urealyticum (Uu) and mycoplasma hominis (Mh) were 43.56 % (142 cases), 33.74 % (110 cases), and 4.29 % (14 cases) respectively, and the positive rate for Uu + Mh was 5.52 % (18 cases). For the female patients, the positive rate was 52.19 % (228 cases), which was significantly higher than that of the male (23.47 %, 98 cases). Drug sensitivity tests indicated that mycoplasma showed drug tolerance to those common antibiotics in various degrees. Conclusion: Mycoplasma is a major pathogen of nongonococcal urethritis, and has developed drug tolerance to common antibiotics in various degrees. For this reason, clinical administration of antibiotics should be made in accordance with drug test results and be applied rationally. ......
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