骨髓基质细胞__(期刊论文)

胎兔骨髓基质细胞与聚β羟基丁酯(PHB)复合物修复骨缺损的实验研究

http://www.100md.com 《第四军医大学学报》 2005年第4期

骨髓基质细胞,,骨髓基质细胞；聚β羟基丁酯；骨代用品；生物医学工程,1材料和方法,2结果,3讨论,【参考文献】

     Experimental study of BMSCPHB complex in reconstructing bone defect

    LIU LiPing1,GAO ZhuoPing1,WU JingHua2,FAN MengYun1,AI YuFeng2,PENG Pai2

    1Department of Otorhinolaryngology,Xian Fourth Municipal Hospital,Xian 710004,China,2Department of Plastic Surgery,Xijing Hospital,Fourth Military Medical University,Xian 710033,China

    【Abstract】 AIM: To study the bone formation of BMSCPHB (bone marrow stromal cellspolyβhydroxybytyrate) complex in rabbit and to screen out the best possible human tissueengineered bone.METHODS: BMSC was first cultured on the PHB material surface to form the BMSCPHB complex and then the complex was implanted into rabbit mandibular bone.PHB materials without BMSC were implanted as control.The bone formation was studied respectively after 4 weeks and 8 weeks by HE staining,electron microscopy and Xray.RESULTS: Bone formation was found on the surface of PHB after 4 weeks,while no bone formation was found in the control group.CONCLUSION: BMSCPHB complex is an ideal tissueengineered bone to reconstruct bone defect. ......

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