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孙会品 孙喜庆 王冰 姚永杰 耿捷 石菲
失重模拟,,失重模拟；顺应性；静脉；对抗,1材料和方法,2结果,3讨论,【参考文献】
Effects of intermittent 45° headup tilt on compliance of jugular vein and mesenteric vein in rabbits after simulated weightlessness
SUN HuiPin, SUN XiQing, WANG Bing, YAO YongJie, GENG Jie, SHI Fei
Department of Aerospace Biodynamics, School of Aerospace Medicine, Fourth Military Medical University, Xian 710033, China
【Abstract】 AIM: To observe the effects of simulated weightlessness and intermittent headuptilt 45° on the compliance of jugular and mesenteric vein in rabbits. METHODS: Twentyfour healthy male rabbits were randomly divided into three groups: control group, simulated weightlessness group and countermeasure group, with 8 rabbits in each group. Simulated weightlessness group kept headdown tilt for 21 d. The countermeasure group kept headup tilt 2 h every day during the 21 d headdown tilt. After 21 d experiment, the compressiondisplacement relationship of jugular and mesenteric vein strips and rings was observed. RESULTS: With the same compression, the displacement of jugular vein in the simulated weightlessness group decreased significantly compared with that in control group (P<0.05 or P<0.01) and the displacement of mesenteric vein in simulated weightlessness group increased significantly compared with that control group (P<0.05). With the same compression, the displacement of both jugular vein and mesenteric vein in countermeasure group had no obvious difference from that of control group. With the same compression, the displacement of jugular vein in countermeasure group increased significantly compared with that in weightlessness group, but the displacement of mesenteric vein decreased significantly (P<0.05). CONCLUSION: A twentyoneday simulated weightlessness may lead to a significant decrease of jugular venous compliance and an increase of mesenteric venous compliance in rabbits. Training of 45° headup tilt 2 h per day can counteract the effects of simulated weightless on the mesenteric and jugular venous compliance. ......
SUN HuiPin, SUN XiQing, WANG Bing, YAO YongJie, GENG Jie, SHI Fei
Department of Aerospace Biodynamics, School of Aerospace Medicine, Fourth Military Medical University, Xian 710033, China
【Abstract】 AIM: To observe the effects of simulated weightlessness and intermittent headuptilt 45° on the compliance of jugular and mesenteric vein in rabbits. METHODS: Twentyfour healthy male rabbits were randomly divided into three groups: control group, simulated weightlessness group and countermeasure group, with 8 rabbits in each group. Simulated weightlessness group kept headdown tilt for 21 d. The countermeasure group kept headup tilt 2 h every day during the 21 d headdown tilt. After 21 d experiment, the compressiondisplacement relationship of jugular and mesenteric vein strips and rings was observed. RESULTS: With the same compression, the displacement of jugular vein in the simulated weightlessness group decreased significantly compared with that in control group (P<0.05 or P<0.01) and the displacement of mesenteric vein in simulated weightlessness group increased significantly compared with that control group (P<0.05). With the same compression, the displacement of both jugular vein and mesenteric vein in countermeasure group had no obvious difference from that of control group. With the same compression, the displacement of jugular vein in countermeasure group increased significantly compared with that in weightlessness group, but the displacement of mesenteric vein decreased significantly (P<0.05). CONCLUSION: A twentyoneday simulated weightlessness may lead to a significant decrease of jugular venous compliance and an increase of mesenteric venous compliance in rabbits. Training of 45° headup tilt 2 h per day can counteract the effects of simulated weightless on the mesenteric and jugular venous compliance. ......