【摘要】 目的 探讨溃疡性结肠炎(UC)患者的临床特征，总结中西医结合治疗UC的经验。方法 回顾性分析本院47例UC患者的临床表现、内镜检查及病理活检资料，治疗方案采用口服西药辅以中药灌肠。 结果 初发17例，反复发作21例，慢性持续9例，轻、中度病变占76.6%，患者多处于30～50岁之间(59.6%)。临床表现以黏液便、脓血便、腹泻、腹痛为主，肠镜下主要显示黏膜充血、水肿、糜烂、溃疡等病变，多为直乙结肠炎(31.9%)和左半结肠炎(36.2%)，病理活检100%患者均表现为弥漫性炎性细胞浸润。本组治愈36例，好转6例，无效5例，总有效率为89.4%。 结论 结肠镜检查对UC的诊断有重要意义，UC患者一般病情较轻，但若不进行有效治疗则易反复发作，本研究采用的中西医结合方案有良好的临床效果。

    【关键词】 溃疡性结肠炎；临床特征；中医；结合

    【Abstract】 Objective To review the clinical features of ulcerative colitis (UC) and our experience in treatment for it. Methods Medical records of 47 patients with UC, such as clinical situation, endoscopic and pathological results were analyzed retrospectively. They all received western medicine supported with enema in traditional Chinese medicine. Results There were 17 cases of initial occurrence, 21 cases of chronic recurring and 9 cases of long lasting. The ratio of mild-to-moderate UC was 76.6% and 59.6% of the patients were aged from 30 to 50 years. The clinical features of UC were abdominal pain, diarrhea mixed with pus, blood, and mucus. Endoscopy indicated edema, hyperemia, erosions and ulcerations in the mucosa, and 31.9% of cases were proctosigmoiditis, 36.2% were colitis of the left hemicolon. Biopsies from 100% of patients showed diffuse inflammative infiltration. After therapy, 36 cases healed, 6 cases improved, and 5 cases had no changes. Conclusion Colonoscopy is important for diagnosis of UC. Generally, UC is mild or moderate, but tends to recur without efficient treatment. The outcome of western and traditional Chinese medicine for UC in this study was ideal. ......