中西医结合防治重症急性胰腺炎继发感染48例分析
重症急性胰腺炎,,重症急性胰腺炎；继发感染；中西医结合；大黄；芒硝,1临床资料,2结果,3讨论,参考文献：
摘要：目的 观察中西医结合防治重症急性胰腺炎继发感染的临床疗效。方法 96例患者随机分为对照组(n=48)和治疗组(n=48)。两组均给予常规治疗，治疗组早期加用生大黄灌肠和芒硝腹部外敷，观察两组主要临床指标、血浆TNFα、IL6和LPS含量及胃肠道功能衰竭、胰腺继发感染发生率和病死率的变化。结果 治疗组较对照组主要临床观察指标恢复时间明显缩短，差异有显著性(P<0.05)；血浆TNFα、IL6和TPS含量明显降低，差异有显著性(P<0.05)；胃肠道功能衰竭、胰腺继发感染发生率明显减少，病死率有所下降，但差别无显著性(P>0.05)。结论 生大黄灌肠和芒硝腹部外敷促进了胃肠道功能的早期恢复，保护了肠道屏障，降低了肠源性细菌和内毒素移位，减轻了全身炎症反应和胰腺继发感染的机会。关键词：重症急性胰腺炎；继发感染；中西医结合；大黄；芒硝
Analysis of Curative Effect of Combined Chinese and Western Medicine on 48 Patients Suffered
from Severe Acute Pancreatitis with Secondary Infection
ZENG Xiangming,WANG Daihong,DING Youming
(Department of Surgery,People’s Hospital of Jiayu County,Jiayu Hubei 437200,China)
ABSTRACT: Objective To observe the clinical curative effect of integrative Chinese and western medicine on severe acute pancreatitis (SAP) with secondary infection.Methods 96 caese with SAP were divided randomly into approach group(n=48)and control group (n=48).Both group were given routine western medicine,but in approach group the patients were additionally administered with Rhubarb and Mangxiao.Their main clinical signs were observed.The plasma levels of TNFa,IL6 and LPS were examined.The incidence of gastrointestinal failure,secondary infection and mortality were also investigated.Results The incidence and duration of main clinical signs,gastrointestinal failure and secondary infection in approach group were significantly lower than those in control group.The plasma levels of TNFa,IL6 and LPS in treatment group decreased sharply.Although the overall mortality in approach group was also lower than that in control group,there was not statistical difference between two group(P>0.05).Conclusion Rhubarb and Mangxiao could promote the early recovery of gastrointestinal function and protect the but barrier,which may decrease intestinal endotoxin translocation,relieve systemic inflammatory reation and reduce the incidence of secondary infection. ......
您现在查看是摘要页，全文长 7431 字符。