系统性红斑狼疮21例临床分析
系统性红斑狼疮,,系统性红斑狼疮;肾损;临床分析,1临床资料,2结果,3讨论,参考文献:
摘要：目的 探讨系统性红斑狼疮(SLE)肾损的发病特点。方法 对21例SLE患者进行进行回顾性分析。结果 肾损组中面部红斑(71.4%)、血液系统损害(71.4%)、关节痛(71.4%)、发热(57.1%)、口腔溃疡(50.0%)、肌肉痛(35.7%)、浆膜炎(19.0%)、神经症状(14.3%)等肾外表现和抗双链DNA抗体(57.1%)、抗SSA抗体(85.7%)、抗SSB抗体(35.7%)、抗核小体抗体(42.3%)、抗核糖体P蛋白抗体(35.7%)、血清补体C3(71.4%)、血清补体C4(78.6%)、血沉(78.6%)等免疫学特征阳性发生率较无肾损组有明显升高，但没有统计学差异(P>0.05)。结论 SLE肾损患者的肾外表现和免疫学特征复杂，但仍有一定规律。关键词：系统性红斑狼疮;肾损;临床分析
Clinical Analysis of 21 Patients with Systemic Lupus Erythematosus
ZENG Fanqi， WANG Xianfeng ，LEI Shuisheng, et al
(Department of Dermatology,Union Hospital,Huazhong University of Science and Technology,Wuhan Hubei 430022,China)
ABSTRACT:Objective To study the clinical characteristic of renal damage caused by systemic lupus erythematosus(SLE). Methods Retrospective study to 21 patients with SLE.Results The manifestations in the group with renal damage were face erythema(71.4%),hematological damage (71.4%),arthralgia(71.4%),fever(57.1%),oral ulcer(50.0%),myodynia(35.7%),hydrohymenitis(19.0%)and symptoms of nervous system(14.3%),which were more heightened than those in the other group without renal damage . The immunologic features of renal damage were antidsDNA antibody(57.1%) ......
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