摘要：目的：观察岩舒注射配合肝动脉化疗栓塞治疗中晚期原发性肝癌的疗效。方法：将68例中晚期原发性肝癌患者随机分为两组：治疗组35例，用岩舒注射液配合肝动脉化疗栓塞治疗；对照组33例，单纯用肝动脉化疗栓塞治疗。结果：治疗组与对照组的近期有效率分别为34.3%和27.3%(P>0.05)，KPS评分改善有效率分别为65.7%和30.3%(P<0.05)。治疗组在肝功能损害、上腹疼痛、食欲下降及发热的发生率均明显低于对照组，差异有显著性统计学意义(P<0.05)，而白细胞下降和恶心、呕吐的发生率略低于对照组，差异无显著性统计学意义(P>0.05)。结论：岩舒注射液配合肝动脉化疗栓塞治疗中晚期原发性肝癌，可提高患者生活质量，减轻不良反应，值得临床推广使用。

    关键词： 岩舒注射液； 肝动脉化疗栓塞； 原发性肝癌

    Clinical Observation On Advanced Primary Hepatic Carcinoma Treated by Yanshu Injection Combined with Transcatheter Arterial Chemoembolization

    HUANG Rui-wen, CHEN Si-xian, HUANG Xiao-ping, et al

    (The Central Hospital of Guangdong Province Agricultural Reclamation, Guangdong Zhanjiang 524002, China)

    Abstract： Objective: To observe the efficacy of Yanshu injection combined with transcatheter arterial chemoembolization (TACE) in treatment of advanced primary hepatic carcinoma (HC).Method:68 patients with advanced HC were randomized into two groups:treatment group of 35 cases with Yanshu injection and TACE and control group of 33 cases with TACE alone. Result: Effective rate was 34.3% and 27.3%(P>0.05), rate of KPS improvement was 65.7% and 30.3%(P<0.05), of treatment group and control group respectively. Frequencies of hypohepatia, epigastric pain, poor appetite and fever were much lower(P<0.05),and of leukocytopenia and vomiting, a little lower (P>0.05), in treatment group,than those of control group. Conclusion: In treatment of patients with advanced HC, Yanshu injection with TACE could improve quality of life and reduce adverse effect, so as to deserve wider application. ......